The Endogenous Brain

Abstract

Synaptic communication, nonsynaptic diffusion neurotransmission and glial activity each update the morphology of the other two. These interactions lead to an endogenous structure of causal entailment. It has internal ambiguities rendering it incomputable. The entailed effects are bizarre. These include abduction of novelty in response to conflicting cues, a resolution of the seeming conflict between freewill and determinism, and anticipatory behavior. Such inherent ambiguity of the causal entailment structure does not preclude the implementation of brain-like activities artificially. Although an algorithm is incapable of neuromimetically reproducing self-referential character of the brain, there is a currently-feasible strategy for wiring a "human in the loop" to use the cognitive powers of anticipation and unconscious integration to provide dramatic improvement in the operation of large engineered systems.

Topology and Life Redux: Robert Rosen’s Relational Diagrams of Living Systems

“…241-243). Comparison of recent experimental results in neurophysiology shows that a similar impredicatively organized structure of closure to efficient cause in the structure of communications in the brain (Kercel 2004b). 3 This answers two of the questions posed in the opening paragraph.…”

“…The essential point of Kercel's endogenous brain paper(Kercel 2004b) was to show the circular hierarchy of synaptic, diffusive, and glial communications circuits. A critical detail that was omitted from that paper was the character of the hierarchy.…”

Complexity Science as an Aspect of the Complexity of Science

“…The work of Bach-y-Rita as interpreted by Kercel [12,13] and others goes tom the heart of many modern controversies. Their interpretation of real experiments involving the sensory behavior of humans is shaking quite a few foundations.…”

Exploring the Temporal Consequences of Chasing the Elements in Rosen's Relational Diagrams

“…Mathematically speaking, no such counter examples are possible [5]. The concepts in this paper do not challenge the idea of endogenous or ambiguous systems as a way to investigate the closed to efficient cause principle [6].…”