The endocrine regulation network of growth hormone synthesis and secretion in fish: Emphasis on the signal integration in somatotropes

Li, Wensheng; Lin, Haoran

doi:10.1007/s11427-010-0084-6

Cited by 27 publications

(14 citation statements)

References 129 publications

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“…Furthermore, we also discovered genes that regulate GH and IGFs, such as the growth hormone releasing hormone (GHRH), pituitary adenylate cyclase-activating polypeptide (PACAP), somatostatins, insulin-like growth factor-binding proteins (IGFBP) ( Text S2 ). GHRH and PACAP are the main regulators that promote GH release, while somatostatins play an inhibitory role [46] . IGFBP act as the carrier proteins for IGF [47] .…”

Section: Resultsmentioning

confidence: 99%

Transcriptome Analysis of the Trachinotus ovatus: Identification of Reproduction, Growth and Immune-Related Genes and Microsatellite Markers

et al. 2014

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BackgroundThe Trachinotus ovatus (Teleostei, Carangidae) is an economically important marine fish species in the world. However, the lack of genomic information regarding this species limits our understanding of the genetics and biological mechanisms in Trachinotus ovatus. In this study, high throughput transcriptome sequencing was used to obtain comprehensive genomic information in Trachinotus ovatus.Principal FindingsTranscriptome sequencing was performed by using Illumina paired-end sequencing technology. The 98,534,862 high quality reads were yielded, and were de novo assembled into 156,094 unigenes with an average sequence length of 1179 bp. Transcriptome annotation revealed that 75,586 and 67,923 unigenes were functionally annotated in the NCBI non-redundant database and Swiss-Prot protein database, respectively. Functional analysis demonstrated that 67,923 unigenes were grouped into 25 Cluster of Orthologous Groups (COG) functional categories, 37,976 unigenes were clustered into 61 Gene Ontology (GO) terms, and 38,172 unigenes were assigned to 275 different Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. Based on the transcriptome dataset, a large number of unigenes associated with reproduction, growth and immunity were identified. Furthermore, a total number of 38,794 simple sequence repeats (SSRs) were discovered and 16 polymorphic loci were characterized in Trachinotus ovatus.Conclusion/SignificanceThe present study is the first transcriptome analysis of a fish species belonging to the genus Trachinotus and provides a valuable genomic resource for novel gene discovery, gene expression and regulation studies, and the identification of genetic markers in Trachinotus ovatus and the other fish of the genus Trachinotus.

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Section: Resultsmentioning

confidence: 99%

Transcriptome Analysis of the Trachinotus ovatus: Identification of Reproduction, Growth and Immune-Related Genes and Microsatellite Markers

et al. 2014

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“…In this cascade, gonadotropin-releasing hormones (GnRHs) produced by hypothalamus are found to be the primary neuropeptides, and gonadotropic hormones (GtHs) synthesized and released by pituitary are found to lead ovaries or testicles to produce mature eggs or sperms, whereas dopamine (DA) produced by pituitary has been found to exhibit an inhibiting effect on the functions of GnRHs [62][63][64]. Multiple GtHs have been reported by Chinese scientists in groupers [65] and Chinese sturgeon (Acipenser sinensis) [66].…”

Section: Reproduction Trait and Candidate Reproductionrelated Genesmentioning

confidence: 99%

Molecular basis and genetic improvement of economically important traits in aquaculture animals

2012

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Aquaculture has been believed to be a major Chinese contribution to the world. In recent 20 years, genome and other genetic technologies have promoted significant advances in basic studies on molecular basis and genetic improvement of aquaculture animals, and complete genomes of some main aquaculture animals have been sequenced or announced to be sequenced since the beginning of this century. Here, we review some significant breakthrough progress of aquaculture genetic improvement technologies including genome technologies, somatic cell nuclear transfer and stem cell technologies, outline the molecular basis of several economically important traits including reproduction, sex, growth, disease resistance, cold tolerance and hypoxia tolerance, and present a series of candidate trait-related genes. Finally, some application cases of genetic improvement are introduced in aquaculture animals, especially in China, and several development trends are highlighted in the near future.

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“…Steroid and steroid hormones have been extensively studied during sex determination and differentiation in vertebrates (Ramsey and Crews 2009;Nakamura 2010Nakamura , 2013. In teleosts, a close connection between sexual dimorphism, reproduction, and growth has been observed (Li and Lin 2010;Chen et al 2013a). In transgenic common carp, inhibiting GnRH synthesis could significantly reduce gonadal development (Hu et al 2007).…”

Section: Transcriptome Sequencing and Assemblymentioning

confidence: 99%

A Comprehensive Transcriptome Provides Candidate Genes for Sex Determination/Differentiation and SSR/SNP Markers in Yellow Catfish

Chen

Mei

et al. 2014

Mar Biotechnol

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Sex dimorphic growth pattern has significant theory and application implications in fish. Recently, a Y-and Xspecific allele marker-assisted sex control technique has been developed for mass production of all-male population in yellow catfish (Pelteobagrus fulvidraco), but the genetic information for sex determination and sex control breeding has remained unclear. Here, we attempted to provide the first insight into a comprehensive transcriptome covering multiple tissues from XX females, XY males, and YY super-males of yellow catfish by using 454 GS-FLX platform, for a better assembly and gene coverage. A total of 1,202,933 high quality reads (about 540 Mbp) were obtained and assembled into 28,297 contigs and 141,951 singletons. BLASTX searches against the NCBI non-redundant protein database (nr) led a total of 52,564 unique sequences including 18,748 contigs and 33,816 singletons to match 25,669 known or predicted unique proteins. All of them with annotated function were categorized by gene ontology (GO) analysis, and 712 were assigned to reproduction and reproductive process. Some potential genes relevant to reproductive system including steroid hormone biosynthesis and GnRH (gonadotropin-releasing hormone) signaling pathway were further identified by Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis; and at least 21 sex determination and differentiation-related genes, such as Dmrt1, Sox9a/b, Cyp19b, WT1, and AMH were identified and characterized. Additionally, a total of 82,794 simple sequence repeats (SSRs), 26,450 single nucleotide polymorphisms (SNPs), and 4,145 insertions and deletions (INDELs) were revealed from the transcriptome data. Therefore, the current transcriptome resources highlight further studies on sex-control breeding in yellow catfish and will benefit future studies on reproduction and sex determination in teleost fish.

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The endocrine regulation network of growth hormone synthesis and secretion in fish: Emphasis on the signal integration in somatotropes

Cited by 27 publications

References 129 publications

Transcriptome Analysis of the Trachinotus ovatus: Identification of Reproduction, Growth and Immune-Related Genes and Microsatellite Markers

Transcriptome Analysis of the Trachinotus ovatus: Identification of Reproduction, Growth and Immune-Related Genes and Microsatellite Markers

Molecular basis and genetic improvement of economically important traits in aquaculture animals

A Comprehensive Transcriptome Provides Candidate Genes for Sex Determination/Differentiation and SSR/SNP Markers in Yellow Catfish

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