“…Moreover, the levels of endocannabinoids, which are normally found at low concentrations in the brain, dramatically increase upon neuronal injury (Berger et al, 2004; Hansen et al, 2001; Panikashvili et al, 2001), suggesting that endocannabinoids provide an endogenous neuroprotective system (van der Stelt and Di Marzo, 2005). The effects of ECS are crucial for restoring normal functioning of CNS synapses and maintaining the viability of neurons during pathological processes associated with impaired regulation of their neurotransmitter function (Khaspekov and Bobrov, 2006). ECS is emerging as a potential target for therapy after neonatal hypoxia.…”