The emerging role of Piezo1 in the musculoskeletal system and disease
Lei Lei,
Zhenkang Wen,
Mingde Cao
et al.
Abstract:Piezo1, a mechanosensitive ion channel, has emerged as a key player in translating mechanical stimuli into biological signaling. Its involvement extends beyond physiological and pathological processes such as lymphatic vessel development, axon growth, vascular development, immunoregulation, and blood pressure regulation. The musculoskeletal system, responsible for structural support, movement, and homeostasis, has recently attracted attention regarding the significance of Piezo1. This review aims to provide a … Show more
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