The emerging role of magnetic resonance imaging and multidetector computed tomography in the diagnosis of dilated cardiomyopathy

Slavich, Massimo; Florian, Anca; Bogaert, Jan

doi:10.1007/s13244-011-0101-8

Cited by 5 publications

(5 citation statements)

References 101 publications

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“…Genetic inheritance is likely to play a role in the development of the disease in 20 to 35% of patients, but also acquired conditions such as metabolic abnormalities, inflammatory and infectious processes, neuromuscular diseases and a large variety of cardiotoxic agents (chemotherapeutic agents, alcohol, illicit drugs) can lead to DCM (Slavich et al, 2011). DCM onset is slow and can appear at any age, with most patients being 30 to 50 years old.…”

Section: Discussionmentioning

confidence: 99%

Torasemide reduces dilated cardiomyopathy, complication of arrhythmia, and progression to heart failure

Han¹,

Guo²,

Lin³

et al. 2014

Genet. Mol. Res.

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ABSTRACT. The aim of this study was to analyze the incidence and types of arrhythmia and their relationship with the severity and prognosis of chronic heart failure (CHF) in patients with dilated cardiomyopathy (DCM), and to investigate the therapeutic effect of torasemide versus furosemide on CHF and incidence of arrhythmia. DCM patients with NYHA cardiac function II-IV were continuously monitored using a 24-h dynamic electrocardiogram (Holter), and arrhythmia incidence was analyzed by computer automatic analysis combined with manual assessment. In total, 125 participants were evenly divided into two groups: torasemide group which received 10 mg oral torasemide once daily) and regular anti-heart failure treatment (N = 65), and furosemide group which received torasemide (20 mg once daily orally) and regular antiheart failure treatment (N = 60). Another 60 normal healthy persons served as the normal control group. Incidence and severity of arrhythmia increased when degree of CHF was elevated. Size of left atrium was related to atrial fibrillation and size of left ventricle was related to malignant arrhythmia. At 3 months after treatment, cardiac function in both groups improved and incidence and severity of arrhythmia in both groups were reduced. However, left ventricular ejection fraction (LVEF) was higher in the torasemide group than in the furosemide group, while incidence of arrhythmia was lower in the torasemide group. Arrhythmias frequently occurred in patients with DCM and HF. Type of cardiac arrhythmia is closely related to ventricular enlargement and cardiac function grade. Torasemide is better for improving cardiac function to reduce arrhythmia and CHF compared to furosemide.

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Section: Discussionmentioning

confidence: 99%

Torasemide reduces dilated cardiomyopathy, complication of arrhythmia, and progression to heart failure

Han¹,

Guo²,

Lin³

et al. 2014

Genet. Mol. Res.

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“…It has been reported that CCTA can also identify prognostically important nonobstructive CAD, such as vascular spasm angina ( 28 , 29 ). CCTA is becoming a frontline strategy for chest pain patients and has been applied in the diagnosis of dilated cardiomyopathy ( 30 , 31 ). CCTA might be used in conjunction with echocardiography to exclude cardiac sarcoidosis.…”

Section: Discussionmentioning

confidence: 99%

Identifying the cause of cardiac arrest through coronary computed tomography angiography with high heart rate under venoarterial extracorporeal membrane oxygenation support: a case description

Wang,

Liu,

et al. 2024

Quant Imaging Med Surg

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“…Chamber enlargement is the first compensatory step aiming to maintain an appropriate stroke volume (SV) as shown by the Frank–Starling mechanism. 7 Above a critical sarcomere stretch, the efficiency of interaction between actin and myosin filaments decreases, causing eccentric ventricular hypertrophy, with decreased wall thickness to chamber diameter ratio and increased ventricular sphericity resulting in impairment of SV. These changes cause an increase in myocardial wall stress with increased oxygen demand and subsequent worsening of the LV systolic performance.…”

Section: Discussionmentioning

confidence: 99%

“…The LV enlargement further dilates the mitral valve ring, dislocates the papillary muscles, and impairs leaflet coaptation thereby causing mitral valvular regurgitation and putting additional volume load on the already dilated ventricle. 7 This in turn will lead to further lowering of EF by compounding the failure.…”

Section: Discussionmentioning

confidence: 99%

“…Contrast-enhanced CMR (CECMR) enables the detection and characterization of myocardial damage. 7 The chief advantage of CMR imaging is its excellent spatial resolution and multiplanar imaging capability which can provide details of cardiac chamber anatomy with simultaneous information about the status of myocardial perfusion and about the impairment of diastolic and systolic functions.…”

Section: Introductionmentioning

confidence: 99%

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Diagnostic Role of Cardiovascular Magnetic Resonance Imaging in Dilated Cardiomyopathy

Singla

Mehra

Garga

2021

Indian Journal of Radiology and Imaging

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Aims The purpose of the study was to compare the accuracy of cardiac magnetic resonance (CMR) with echocardiography for the evaluation of ventricular dysfunction in patients of dilated cardiomyopathy (DCM). Further, we evaluated the potential of CMR for myocardial tissue characterization. Design Prospective observational. Materials and Methods A total of 30 patients with suspected DCM prospectively underwent cardiac magnetic resonance (MR) using a 1.5 Tesla MR scanner, with appropriate phased-array body coils. Dynamic sequences after injection of 0.1 mmol/kg of body weight of gadolinium-based intravenous contrast (Magnevist) were acquired for each patient, after which delayed images were obtained at an interval of 12 to 15 minutes. Myocardial tagging was performed in all patients for assessment of wall motion abnormalities. Each MR examination was interpreted with two radiologists for chamber dimensions and ventricular dysfunction as well as morphologic characteristics with disagreement resolved by consensus. All patients included in the study were taken up for MR evaluation after cardiological evaluation through echocardiography and the results for both the studies were compared. Data were analyzed through standard statistical methods. Conclusion CMR is a comprehensive diagnostic tool, which can estimate the ventricular function more precisely than echocardiography. CMR reliably differentiates between ischemic and nonischemic etiologies of DCM based on patterns of late gadolinium enhancement (LGE) and based on the presence or absence of LGE, which helps to estimate the degree of myocardial fibrosis. Thereby it can be a useful tool in establishing risk stratification, predicting prognosis, and thus instituting appropriate therapy in DCM patients.

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The emerging role of magnetic resonance imaging and multidetector computed tomography in the diagnosis of dilated cardiomyopathy

Cited by 5 publications

References 101 publications

Torasemide reduces dilated cardiomyopathy, complication of arrhythmia, and progression to heart failure

Torasemide reduces dilated cardiomyopathy, complication of arrhythmia, and progression to heart failure

Identifying the cause of cardiac arrest through coronary computed tomography angiography with high heart rate under venoarterial extracorporeal membrane oxygenation support: a case description

Diagnostic Role of Cardiovascular Magnetic Resonance Imaging in Dilated Cardiomyopathy

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