The emerging role of epitranscriptome in shaping stress responses in plants

Dhingra, Yashika; Gupta, Shitij; Gupta, Vaishali; Agarwal, Manu; Katiyar-Agarwal, Surekha

doi:10.1007/s00299-023-03046-1

Cited by 4 publications

(1 citation statement)

References 205 publications

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“…Global m 6 A patterns in plant transcriptomes are highly dynamic, and change in response to light ( Artz et al , 2023 , Preprint), temperature ( Liu et al , 2020 ; S. Wang et al , 2023 ), salinity ( Anderson et al , 2018 ; Kramer et al , 2020 ), and drought ( Zhang et al , 2021 ). In agreement with these findings, mutants in many m 6 A writers, readers, and erasers—proteins that incorporate, recognize, and remove m 6 A, respectively—impact the plant’s sensitivity to these environmental signals ( Dhingra et al , 2023 ). FIONA1 (FIO1) is an Arabidopsis m 6 A methyltransferase that installs m 6 A in U6 small nuclear RNAs, but also in a small number of polyadenylated RNAs ( Wang et al , 2022 ).…”

Section: Rna Modificationsmentioning

confidence: 70%

Untranslated yet indispensable—UTRs act as key regulators in the environmental control of gene expression

Hardy,

Balcerowicz

2024

Journal of Experimental Botany

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To survive and thrive in a dynamic environment, plants must continuously monitor their surroundings and adjust their development and physiology accordingly. Changes in gene expression underlie these developmental and physiological adjustments and are traditionally attributed to widespread transcriptional reprogramming. Growing evidence, however, suggests that post-transcriptional mechanisms also play a vital role in tailoring gene expression to a plant’s environment. Untranslated regions (UTRs) act as regulatory hubs for post-transcriptional control, harbouring cis elements that affect an mRNA’s processing, localisation, translation and stability and thereby tune the abundance of the encoded protein. Here, we review recent advances made in understanding the critical function UTRs exert in the post-transcriptional control of gene expression in the context of a plant’s abiotic environment. We summarise the molecular mechanisms at play, present examples of UTR-controlled signalling cascades and discuss the potential that resides within UTRs to render plants more resilient to a changing climate.

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