The emergence of Y-chromosome haplogroup J1e among Arabic-speaking populations

Chiaroni, Jacques; King, Roy; Myres, Natalie M.; Henn, Brenna M.; Ducourneau, Axel; Mitchell, Michael J.; Boëtsch, Gilles; Sheikha, Issa; Lin, Alice A.; Nik-Ahd, Mahnoosh; Ahmad, Jabeen; Lattanzi, F.; Herrera, René J.; Ibrahim, Muntaser E.; Brody, Aaron J.; Semino, Ornella; Kivisild, Toomas; Underhill, Peter A.

doi:10.1038/ejhg.2009.166

Cited by 72 publications

(65 citation statements)

References 32 publications

(32 reference statements)

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“…We assembled a genotyping panel of 16 244 males from 126 Eurasian populations, some of which we report upon for the first time herein and others that we have combined from earlier studies, 22,[29][30][32][33][34][35][36][37][38][39][40][41][42][43][44][45] and updated to a higher level of phylogenetic resolution. All samples were obtained using locally approved informed consent and were de-identified.…”

Section: Population Samplesmentioning

confidence: 99%

The phylogenetic and geographic structure of Y-chromosome haplogroup R1a

Underhill¹,

Poznik²,

Rootsi³

et al. 2014

Eur J Hum Genet

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137

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,23R1a-M420 is one of the most widely spread Y-chromosome haplogroups; however, its substructure within Europe and Asia has remained poorly characterized. Using a panel of 16 244 male subjects from 126 populations sampled across Eurasia, we identified 2923 R1a-M420 Y-chromosomes and analyzed them to a highly granular phylogeographic resolution. Whole Y-chromosome sequence analysis of eight R1a and five R1b individuals suggests a divergence time of B25 000 (95% CI: 21 300-29 000) years ago and a coalescence time within R1a-M417 of B5800 (95% CI: 4800-6800) years. The spatial frequency distributions of R1a sub-haplogroups conclusively indicate two major groups, one found primarily in Europe and the other confined to Central and South Asia. Beyond the major European versus Asian dichotomy, we describe several younger sub-haplogroups. Based on spatial distributions and diversity patterns within the R1a-M420 clade, particularly rare basal branches detected primarily within Iran and eastern Turkey, we conclude that the initial episodes of haplogroup R1a diversification likely occurred in the vicinity of present-day Iran.

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Section: Population Samplesmentioning

confidence: 99%

The phylogenetic and geographic structure of Y-chromosome haplogroup R1a

Underhill¹,

Poznik²,

Rootsi³

et al. 2014

Eur J Hum Genet

Self Cite

137

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“…The hg G individuals in Supplementary Table S1 were either first genotyped for this study or updated to present phylogenetic resolution from earlier studies. 2,4,10,11,13,16,[18][19][20][21][22][23][24][25][26][27] All hg G (M201-derived) samples were genotyped in a hierarchical manner for the following binary markers: M285, P20, P287, P15, L91 P16, M286, P303, U1, L497, M406, Page19, M287 and M377. Specifications for most markers have been previously reported, 1,17,28 ISOGG 2011 (http://www.isogg.org/tree/).…”

Section: Methodsmentioning

confidence: 99%

Distinguishing the co-ancestries of haplogroup G Y-chromosomes in the populations of Europe and the Caucasus

Rootsi

Myres²,

Lin

et al. 2012

Eur J Hum Genet

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Haplogroup G, together with J2 clades, has been associated with the spread of agriculture, especially in the European context. However, interpretations based on simple haplogroup frequency clines do not recognize underlying patterns of genetic diversification. Although progress has been recently made in resolving the haplogroup G phylogeny, a comprehensive survey of the geographic distribution patterns of the significant sub-clades of this haplogroup has not been conducted yet. Here we present the haplogroup frequency distribution and STR variation of 16 informative G sub-clades by evaluating 1472 haplogroup G chromosomes belonging to 98 populations ranging from Europe to Pakistan. Although no basal G-M201* chromosomes were detected in our data set, the homeland of this haplogroup has been estimated to be somewhere nearby eastern Anatolia, Armenia or western Iran, the only areas characterized by the co-presence of deep basal branches as well as the occurrence of high sub-haplogroup diversity. The P303 SNP defines the most frequent and widespread G sub-haplogroup. However, its sub-clades have more localized distribution with the U1-defined branch largely restricted to Near/Middle Eastern and the Caucasus, whereas L497 lineages essentially occur in Europe where they likely originated. In contrast, the only U1 representative in Europe is the G-M527 lineage whose distribution pattern is consistent with regions of Greek colonization. No clinal patterns were detected suggesting that the distributions are rather indicative of isolation by distance and demographic complexities.

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“…27,38,[42][43][44][45]39 Previous investigations have found some of these haplogroups, including J1-M267 and J2-M172, to illustrate patterns of distributions that reflect the spread of agriculture and domestication from the Fertile Crescent, 37,45 and recently, the distribution of R1b1b-M269 haplotypes across the Near East and Europe has been proposed to be best explained by a Neolithic dispersal. 44 Of particular prominence in Armenia are haplogroups R1b-M343 and J2-M172, which are detected in Ararat Valley, Gardman and Lake Van at frequencies higher than those observed in any of the Near Eastern populations analyzed in this study.…”

Section: Genetic Support For Neolithic Origins Of the Armenian Populamentioning

confidence: 99%