The electrophysiological response of the dogfish gastric mucosa to extracellular potassium

Transport and electrical phenomena in resting and secreting piglet gastric mucosa.

“…Perhaps the H+ secretary mechanism, especially at the more brisk rates observed here in the TRANSPORT AND PIGLET GASTRIC MUCOSA mammal, is more directly dependent upon the presence of Cl-or cannot be so easily 'uncoupled' from Cl-transport. For instance, toward the latter possibility a very tight, almost obligatory stoicheiometry between H+ and Cl-transport occurs in species such as marine elasmobranchs (Hogben, Brandes & Stevens, 1972) or even in amphibia under specially treated conditions . It is significant that even with the very large changes in unidirectional fluxes both H+ and Cl-transport by short-circuited gastric mucosa were stimulated to nearly the same extent by histamine (cf.…”