The Electroencephalogram in Advanced Senile Dementia*

Müller, H.; Kral, V. A.

doi:10.1111/j.1532-5415.1967.tb02073.x

Cited by 27 publications

(19 citation statements)

References 14 publications

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“…The tracing in Figure 11 was obtained on the same patient two years later and showed some increase of slow activity. Figure 12 is a recent EEG on the same patient, taken five years after admission; it showed only remnants of the sharp activity and a predominance of slow waves, including the biposterior sharp‐and‐slow wave complexes, partly with a 1 to 2 per second rhythm, typically seen in far advanced senile dementia (8). It is remarkable, however, that this woman, even now, is much less apathetic than those senile patients who show such posterior complexes without frontal and central sharp activity.…”

Section: Resultsmentioning

confidence: 99%

Generalized Sharp Activity in the Electroencephalogram of Middle‐aged and Elderly Psychiatric Patients*

Müller

1969

J American Geriatrics Society

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A survey of the electroencephalograms (EEGs) of 510 psychiatric subjects aged 50 or older revealed 41 cases of unusual spontaneous or photically evoked sharp and spiky activity. The EEGs of elderly patients often show generalized sharp activity, usually more intense than in younger subjects. This activity may be an aspect of various types of background rhythm, or it may be partly independent of them. Clinically, these patients tend to manifest psychomotor agitation and other symptoms indicating physical and mental overactivity. At least in patients whose EEGs show intense sharp activity, there can be little doubt about this EEG‐clinical relationship. It appears, therefore, that we are dealing with electrical phenomena which indicate forebrain hyperexcitability and which are associated with a hyperactive state in other parts of the organism.

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Section: Resultsmentioning

confidence: 99%

Generalized Sharp Activity in the Electroencephalogram of Middle‐aged and Elderly Psychiatric Patients*

Müller

1969

J American Geriatrics Society

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“…Epileptiform discharges are rarely observed in EEG patients with AD even if the epileptic seizures are part of the clinical picture [29]. Rae-Grant found epileptiform discharges (sharp waves and spikes) only in 5% of patients [30].…”

Section: Discussionmentioning

confidence: 99%

The value of quantitative EEG in differential diagnosis of Alzheimer's disease and subcortical vascular dementia

Gaweł

Zalewska

Szmidt-Salkowska

et al. 2009

Journal of the Neurological Sciences

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“…In numerous studies the EEG of demented individuals was found to undergo significant changes. However, few studies have been reported which attempt to correlate the degree ofcerebral atrophy with the severity of the EEG abnormalities in mentally deteriorating aging persons (Mundy-Castle et al, 1954;Weiner and Schuster, 1956;Busse and Wang, 1965;Muller and Kral, 1967).…”

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confidence: 99%

Correlation between diffuse EEG abnormalities and cerebral atrophy in senile dementia.

Stefoski¹,

Bergen²,

Fox³

et al. 1976

Journal of Neurology, Neurosurgery & Psychiatry

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SYNOPSIS Thirty-five elderly patients were investigated because of clinical signs of dementia. The presence of diffuse cerebral atrophy, and its severity, were determined by the use of computed tomography (CT scan). All of the patients were also examined by electroencephalography (EEG), and the presence of diffuse abnormalities, especially diffuse slowing, was noted. Specifically, patients with normal or near-normal EEGs were compared with those with severe diffuse slowing. No correlation between the presence or severity of diffuse EEG abnormalities and the degree of cerebral atrophy as measured by CT scan was found. Though the EEG is clearly identifying physiological dysfunction of nerve cells in demented patients it does not appear to be a reliable tool for the prediction of diffuse cerebral atrophy in this population.Senile dementia in association with diffuse cerebral atrophy is one of the problems commonly encountered by the clinical neurologist. In numerous studies the EEG of demented individuals was found to undergo significant changes. However, few studies have been reported which attempt to correlate the degree ofcerebral atrophy with the severity of the EEG abnormalities in mentally deteriorating aging persons (MundyCastle et al., 1954;Weiner and Schuster, 1956;Busse and Wang, 1965;Muller and Kral, 1967).The present study was designed to explore the correlation between these two variables in order to assess whether the EEG might be a reliable tool for the detection of cerebral atrophy in the elderly demented patient. METHODSThirty-five patients over 59 years of age were among a larger group hospitalized on the basis of having clinical signs of dementia. Senile dementia was

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The Electroencephalogram in Advanced Senile Dementia*

Cited by 27 publications

References 14 publications

Generalized Sharp Activity in the Electroencephalogram of Middle‐aged and Elderly Psychiatric Patients*

Generalized Sharp Activity in the Electroencephalogram of Middle‐aged and Elderly Psychiatric Patients*

The value of quantitative EEG in differential diagnosis of Alzheimer's disease and subcortical vascular dementia

Correlation between diffuse EEG abnormalities and cerebral atrophy in senile dementia.

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