The electrical impedance methods in cardiology

Pęczalski, Kazimierz

doi:10.1016/b978-0-12-818614-5.00011-4

Cited by 1 publication

(2 citation statements)

References 15 publications

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“…contractility (Peng et al, 2004) and positive inotropy of the heart muscle (Peczalski, 2021;Thayer et al, 2010). HI was found to be a more reliable contractility metric than PEP (Peng et al, 2004).…”

Section: Metricsmentioning

confidence: 83%

“…The relevance of our findings is supported by prior research that emphasizes the novelty and importance of HI in heart failure. Laboratory experiments with animals have validated HI as a potential index of myocardial contractility (Peng et al, 2004) and positive inotropy of the heart muscle (Peczalski, 2021; Thayer et al, 2010). HI was found to be a more reliable contractility metric than PEP (Peng et al, 2004).…”

Section: Discussionmentioning

confidence: 99%

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Association between PTSD and Impedance Cardiogram‐based contractility metrics during trauma recall: A controlled twin study

et al. 2022

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Post-traumatic stress disorder (PTSD) is an independent risk factor for incident heart failure, but the underlying cardiac mechanisms remained elusive.Impedance cardiography (ICG), especially when measured during stress, can help understand the underlying psychophysiological pathways linking PTSD with heart failure. We investigated the association between PTSD and ICG-based contractility metrics (pre-ejection period (PEP) and Heather index (HI)) using a controlled twin study design with a laboratory-based traumatic reminder stressor.PTSD status was assessed using structured clinical interviews. We acquired synchronized electrocardiograms and ICG data while playing personalized-trauma scripts. Using linear mixed-effects models, we examined twins as individuals and within PTSD-discordant pairs. We studied 137 male veterans (48 pairs, 41 unpaired singles) from Vietnam War Era with a mean (standard deviation) age of 68.5(2.5) years. HI during trauma stress was lower in the PTSD vs. non-PTSD individuals (7.2 vs. 9.3 [ohm/s 2 ], p = .003). PEP reactivity (trauma minus neutral) was also more negative in PTSD vs. non-PTSD individuals (−7.4 vs. −2.0 [ms], p = .009). The HI and PEP associations with PTSD persisted for adjusted models during trauma and reactivity, respectively. For within-pair analysis of eight PTSD-discordant twin pairs (out of 48 pairs), PTSD was associated with lower HI in neutral, trauma, and reactivity, whereas no association was found between PTSD and PEP. PTSD was associated with reduced HI and PEP, especially with

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