The Electrical Conductivity of Blood

Texter, E. Clinton; Hirsch, Frederic G.; Horan, Francis E.; Wood, Lloyd A.; Ballard, William C.; Wright, Irving S.; Starr, Dorothy; Blandin, Benjamin P.

doi:10.1182/blood.v5.11.1036.1036

Cited by 13 publications

(1 citation statement)

References 3 publications

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“…Measuring the total duration of a cell cycle is relatively easy, and can rely on the increase in cell number per time [8][9][10][11], coupled with methods to quantify the proliferative Biology 2022, 11, 718 2 of 16 fraction, such as Ki67 labeling [12,13]. However, measuring the duration of individual stages of the cell cycle is much more challenging.…”

Section: Main 21 Measuring S Phase Durationmentioning

confidence: 99%

S Phase Duration Is Determined by Local Rate and Global Organization of Replication

Greenberg

Simon

2022

Biology

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The duration of the cell cycle has been extensively studied and a wide degree of variability exists between cells, tissues and organisms. However, the duration of S phase has often been neglected, due to the false assumption that S phase duration is relatively constant. In this paper, we describe the methodologies to measure S phase duration, summarize the existing knowledge about its variability and discuss the key factors that control it. The local rate of replication (LRR), which is a combination of fork rate (FR) and inter-origin distance (IOD), has a limited influence on S phase duration, partially due to the compensation between FR and IOD. On the other hand, the organization of the replication program, specifically the amount of replication domains that fire simultaneously and the degree of overlap between the firing of distinct replication timing domains, is the main determinant of S phase duration. We use these principles to explain the variation in S phase length in different tissues and conditions.

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Section: Main 21 Measuring S Phase Durationmentioning

confidence: 99%

S Phase Duration Is Determined by Local Rate and Global Organization of Replication

Greenberg

Simon

2022

Biology

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Quo Vadis, Implanted Fuel Cell?

Shleev

2017

ChemPlusChem

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The road to safe and effective implantable electrical power devices has been long—and the goal has not been reached yet, although a certain amount of scientific and technological progress has been made. This brief review is focused on highlighting the stages of development of implanted fuel cells capable of providing electrical power for running implanted “personal electronics”. The paper starts with early efforts to implant glucose‐burning fuel cells in dogs, and ends with realistic attempts at interfacing a more sophisticated enzymatic glucose/oxygen fuel cell in an actual human blood stream. However, before that, the review deals with thermodynamic aspects of fuel cells, emphasizing the general advantages of these devices. Further steps, which are needed to realize the potential of this technology and which somehow differ from generally accepted ideas, are presented. These next steps are evaluated in the context of theoretically achievable abilities of implantable chemical power sources, which are not as great as many researchers might expect.

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