The elderly patient and postoperative pain treatment

Aubrun, Frédéric; Marmion, Frédéric

doi:10.1016/j.bpa.2006.12.005

Cited by 117 publications

(73 citation statements)

References 82 publications

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“…As the population continues to age, the number of elderly surgical patients will increase. Moreover, the physical function in elderly is declined and the elderly have an increased vulnerability to stressors (Aubrun & Marmion, 2007).…”

Section: Background and Significance Of The Studymentioning

confidence: 99%

“…It is increasingly clear that elderly are at greater risk for pain-related morbidity including physical disability and psychological distress, such as myocardial infarction, respiratory failure, depression, and delirium (Aubrun & Marmion;Gagliese & Melzack, 2006).…”

Section: Background and Significance Of The Studymentioning

confidence: 99%

“…In terms of the respiratory system, unrelieved pain decreases the effective cough reflex and increases atelectases, pneumonia, and hypoxemia (Breivik, 2002;Weetman & Allison, 2006). In addition, unrelieved pain can cause respiratory failure in elderly (Aubrun & Marmion, 2007;Craig, 1981). In the cardiovascular system, unrelieved pain increases heart rate and blood pressure, myocardial oxygen demand and ischaemic events (Breivik), and the risk of developing deep vein thrombosis (Aubrun & Marmion).…”

Section: Impacts Of Unrelieved Postoperative Painmentioning

confidence: 99%

“…Moreover, unrelieved pain can easily cause myocardial infarction in elderly (Aronow, 2003;Aubrun & Marmion). In the gastrointestinal system, unrelieved pain delays gastric emptying time leading to nausea and vomiting, decreases gut motility leading to ileus, and causes poor nutrition leading to delayed tissues healing (Aubrun & Marmion;Macintyre & Ready, 2002;Weetman & Allison).…”

Section: Impacts Of Unrelieved Postoperative Painmentioning

confidence: 99%

“…In the gastrointestinal system, unrelieved pain delays gastric emptying time leading to nausea and vomiting, decreases gut motility leading to ileus, and causes poor nutrition leading to delayed tissues healing (Aubrun & Marmion;Macintyre & Ready, 2002;Weetman & Allison). In the urinary system, unrelieved pain easily causes urinary retention (Breivik).…”

Section: Impacts Of Unrelieved Postoperative Painmentioning

confidence: 99%

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Psychometric properties of pain intensity scales comparing among postoperative adult patients, elderly patients without and with mild cognitive impairment in China

Zhou

Petpichetchian

Kitrungrote

2011

International Journal of Nursing Studies

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In China, there is a lack of studies to generate pain intensity scales to the patients with CI and compare the pain scales in various age groups. Therefore, this study would compare the psychometric properties of the evidence-supported pain intensity scales consisting of the Verbal Descriptor Scale (VDS), the Numeric Rating Scale (NRS), the Faces Pain Scale (FPS), the Numeric Box-21 Scale (BS-21), and the Colored Analogue Scale (CAS) in Chinese postoperative adults varying in ages including the elderly with mild CI. This was a descriptive comparative study and 200 surgical patients were recruited purposively from a university-affiliated hospital with 50 for each group: young adults (age 20 -44 years), middle-aged adults (age 45 -59 years), elderly (age ≥ 60 years) without CI, and elderly (age ≥ 60 years) with mild CI.Participants rated the vividly remembered, current, worst, least, and average pain, and indicated scale preference and simplicity. Scale face validity, concurrent validity, convergent validity, and test-retest reliability at a 3-day interval were assessed. Fisher's exact tests were used to investigate whether face validity was related to different age iv groups and the levels of CI. One-way ANOVA and Kruskal-Wallis test were used to test the differences of concurrent validity, convergent validity, and test-retest reliability of each pain scale among the four groups. Regarding face validity, the FPS was ranked best across the subjects as nearly half of the patients selected it as both the most preferred and simplest and it had low errors; the VDS and the NRS were similar and ranked following the FPS; however, the BS-21 and the CAS were ranked last. The concurrent validity, convergent validity, and test-retest reliability of all five pain scales were supported in use with the four groups. The differences in psychometric properties among the four groups were only found in face validity. The findings support the psychometric properties of all five pain scales for pain assessment in Chinese adults including the elderly with mild CI. However, the FPS appears to be the best scale followed by the VDS and the NRS. ACKNOWLEDGEMENTSIt is impossible to finish this work without the continuous help and love from the people around me. I take this opportunity to give thanks to them for their willing to teach, guidance, help, and care during my master degree study.

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Section: Background and Significance Of The Studymentioning

confidence: 99%

Section: Background and Significance Of The Studymentioning

confidence: 99%

Section: Impacts Of Unrelieved Postoperative Painmentioning

confidence: 99%

Section: Impacts Of Unrelieved Postoperative Painmentioning

confidence: 99%

Section: Impacts Of Unrelieved Postoperative Painmentioning

confidence: 99%

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Psychometric properties of pain intensity scales comparing among postoperative adult patients, elderly patients without and with mild cognitive impairment in China

Zhou

Petpichetchian

Kitrungrote

2011

International Journal of Nursing Studies

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Interventions for preventing delirium in hospitalised non-ICU patients

Siddiqi

Harrison

Clegg

et al. 2016

Cochrane Database of Systematic Reviews

385

407

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Pharmacokinetics of Diclofenac and Hydroxypropyl‐β‐Cyclodextrin (HPβCD) Following Administration of Injectable HPβCD‐Diclofenac in Subjects With Mild to Moderate Renal Insufficiency or Mild Hepatic Impairment

Hamilton

Ernst

Kramer

et al. 2017

Clinical Pharm in Drug Dev

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Given their established analgesic properties, nonsteroidal anti‐inflammatory drugs (NSAIDs) represent an important postoperative pain management option. This study investigated: (1) the effects of mild or moderate renal insufficiency and mild hepatic impairment on the pharmacokinetics (PK) of diclofenac and hydroxypropyl‐β‐cyclodextrin (HPβCD) following administration of the injectable NSAID HPβCD‐diclofenac; and (2) the PK of HPβCD following administration of HPβCD‐diclofenac and intravenous itraconazole formulated with HPβCD in healthy adults. Diclofenac clearance (CL) and volume of distribution (Vz) tended to increase with decreasing renal function (moderate insufficiency versus mild insufficiency or healthy controls). Regression analysis demonstrated a significant relationship between Vz (but not CL or elimination half‐life, t½) and renal function. HPβCD CL was significantly decreased in subjects with renal insufficiency, with a corresponding increase in t½. There were no significant differences in diclofenac or HPβCD PK in subjects with mild hepatic impairment versus healthy subjects. Exposure to HPβCD in healthy subjects following HPβCD‐diclofenac administration was ∼12% of that with intravenous itraconazole, after adjusting for dosing schedule and predicted accumulation (<5% without adjustment). With respect to PK properties, these results suggest that HPβCD‐diclofenac might be administered to patients with mild or moderate renal insufficiency or mild hepatic impairment without dose adjustment (NCT00805090).

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The elderly patient and postoperative pain treatment

Cited by 117 publications

References 82 publications

Psychometric properties of pain intensity scales comparing among postoperative adult patients, elderly patients without and with mild cognitive impairment in China

Psychometric properties of pain intensity scales comparing among postoperative adult patients, elderly patients without and with mild cognitive impairment in China

Interventions for preventing delirium in hospitalised non-ICU patients

Pharmacokinetics of Diclofenac and Hydroxypropyl‐β‐Cyclodextrin (HPβCD) Following Administration of Injectable HPβCD‐Diclofenac in Subjects With Mild to Moderate Renal Insufficiency or Mild Hepatic Impairment

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