2015
DOI: 10.4103/0975-7406.163542
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The efficiency of 2.5% sodium hypochlorite in preventing inoculation of periapical tissues with contaminated patency files: An ex vivo evaluation

Abstract: The purpose of this in vitro study was to analyze the effectiveness of 2.5% sodium hypochlorite (NaOCl) in preventing inoculation of periapical tissue with contaminated patency files. Fifty single-rooted teeth with single canals were used in the study. They were randomly divided into five groups of which two were experimental groups, two positive controls, and one negative control group. After root canal preparation, teeth in Group I (experimental) were filled with 2.5 NaOCl and #15 stainless steel K-files con… Show more

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Cited by 6 publications
(5 citation statements)
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References 11 publications
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“…Root canal disinfection is the essential key to endodontic management. Sodium hypochlorite at 2.5%–5.25% is the irrigant of choice; efficiency is related to the delivery system which must be thin to reach the complex apical regions allowing full disinfection [ 8 , 10 , 24 ]. Considering the complexity of the canal system, full potentiality of the irrigant is required.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Root canal disinfection is the essential key to endodontic management. Sodium hypochlorite at 2.5%–5.25% is the irrigant of choice; efficiency is related to the delivery system which must be thin to reach the complex apical regions allowing full disinfection [ 8 , 10 , 24 ]. Considering the complexity of the canal system, full potentiality of the irrigant is required.…”
Section: Discussionmentioning
confidence: 99%
“…However, sodium hypochlorite (NaOCl) remains the irrigant of choice [ 5 – 7 ] due to its antibacterial nature, dissolving both necrotic and organic matter within the smear layer [ 8 ]. The Scientific Committee Consensus [ 6 , 8 10 ] recommends a concentration of 2.5% to 5.25% of sodium hypochlorite, providing adequate balance between disinfection and toxicity.…”
Section: Introductionmentioning
confidence: 99%
“…17,[18][19][20] Sodium hypochlorite is used for the irrigation of canals because sodium hypochlorite is the most effective irrigant used for canal cleaning because of it is antibacterial property removing the dead tissue including the necrotic one and organic part of the smear layer. 21 The Scientific Committee Consensus, [22][23][24] recommends a concentration of 2.5% to 5.25% of sodium hypochlorite, in order to decrease its toxicity without decreasing its antibacterial effect. GuttaFlow bioseal combined both Guttapercha and sealer in one product used as a sealer and obturating material.…”
Section: Discussionmentioning
confidence: 99%
“…There are those who view this with concern due to the possibility of bacterial extrusion [34,35], and its subsequent influence on treatment outcome in the light of studies -although rare -that have reported root canal failure due to bacteria found in the periapical area [36]. Two in-vitro studies explored this possibility and reported that when using a patency file in canals filled with NaOCl, this prevented the inoculation of periapical tissue with bacteria [37,38]. How-ever, in these studies, the files were contaminated with only Streptococcus sanguis which does not reflect the diverse bacterial population found in root canals undergoing endodontic treatment, and which may include more resistant bacterial strains [36].…”
Section: Apical Patency and Biological Considerationsmentioning
confidence: 99%