The efficacy of transarterial chemoembolization combined with microwave ablation for unresectable hepatocellular carcinoma: a systematic review and meta-analysis

Wang, Lei; Lin, Nanping; Huang, Qizhen; Zeng, Yongyi; Liu, Jingfeng

doi:10.1080/02656736.2019.1692148

Cited by 22 publications

(13 citation statements)

References 46 publications

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“…In this synthesis of 1 and 2, we utilized [N 3 ] − and [SCN] −1 as a co‐ligand respectively because of the propensity of these ions to bridge adjacent metal centers. Besides this [N 3 ] − and [SCN] −1 also allows the assembly to proliferate to construct the coordination polymers . Accordingly, the reaction of Schiff base (H 2 L 1 ), Cd(II) salts in presence of [N 3 ] − as co‐ligand (in a 1:1:1 stoichiometric ratio) allows the formation of neutral 1D coordination polymer {[Cd 4 (N 3 ) 4 (L 1 ) 2 ].H 2 O} n ( 1 ) (Scheme , Right side).…”

Section: Resultsmentioning

confidence: 99%

“…However, the formation of coordination polymer in a conventional mode still remains a tricky task, since the self‐assembly of such compounds can be affected by some key aspects like the geometry of metal ions, type of organic building blocks, solvent effects, the ratio of metal‐to‐ligand, template effect, and introduction of ancillary ligands . To develop diverse topologies and frameworks of coordination polymers, pseudohalides like azide and thiocyanate are known to perform excellent bridging ligands attributed to their smaller length, rigidity and variety of coordination modes of donor atoms . In addition, metal Zn(II) and Cd(II)) coordination polymers which are derived from pseudohalides like azide and thiocyanate are of contemporary interest because of their unique pale color, higher thermally stability and possible luminescence properties …”

Section: Introductionmentioning

confidence: 99%

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Syntheses, X-ray Crystal Structures, Photoluminescence Properties, Antimicrobial Activities and Hirshfeld Surface of Two New Cd(II) Azide/Thiocyanate Linked Coordination Polymers

Majumdar¹,

Babu

Das

et al. 2017

ChemistrySelect

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The reaction of cadmium(II) acetate salts with multisite coordinated compartmental Schiff base ligand N,N'-Bis(3methoxysalicylidenimino)-1,3-diaminopropane (H 2 L 1 ) in presence of co-lingand azido/thiocyanato afforded two new coordination polymers {[Cd 4 (N 3 ) 4 (L 1 ) 2 ]·H 2 O} n (1), [Cd 4 (SCN) 4 (L 1 ) 2 ] n (2). The obtained compounds, 1 and 2 are 1D and 2D coordination polymers respectively and they have been characterized by IR spectroscopy, UV-vis spectroscopy, elemental analysis, and single-crystal X-ray diffraction. The variation in the extended forms of 1 and 2 is governed by the kind of coligands utilized in the reaction. The complete structural study reveals that, in both cases the fully deprotonated ligand [L 1 ] 2À has utilized all six potential coordination sites to hold a pair of Cd(II) ions. Moreover, [N 3 ] À in 1 is coordinating to metal atom by both trans end-to-end (EE m-1,3) and end-on (EO or m-1,1) mode and [SCN] À is showing only end-to-end (EE m-1,3) coordination mode in 2. The photo luminescent properties and antimicrobial activities of the compounds 1 and 2 were investigated and discussed in details. Upon irradiation with UV light Cd(II) polymeric compounds 1-2 exhibit deep blue emissions of 448 À 451 nm subjected to dimethyl sulfoxide solution due to p!p* intraligand fluorescence. Apart from, as a complementary revelation, intermolecular interactions with respect to percentages of hydrogen bonding in the crystal structures of two Cd(II) polymeric compounds were quantified by Hirshfeld surface and fingerprint plots analysis.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Syntheses, X-ray Crystal Structures, Photoluminescence Properties, Antimicrobial Activities and Hirshfeld Surface of Two New Cd(II) Azide/Thiocyanate Linked Coordination Polymers

Majumdar¹,

Babu

Das

et al. 2017

ChemistrySelect

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“…The heterogeneity was assessed by the χ 2 test and I 2 statistics; P < 0.10 or I 2 > 50% were considered as significant heterogeneity. When the hypothesis of homogeneity was rejected, the fixed-effects model was used to estimate the case with homogeneity, and the random-effects model was used for the cases with significant heterogeneity [26]. Sensitivity analysis was conducted as follows: one study at a time was removed and the remained were re-analyzed to determine whether the results could be affected significantly by single study [27].…”

Section: Discussionmentioning

confidence: 99%

Does additional resection of a positive microscopic ductal margin benefit patients with perihilar cholangiocarcinoma: A systematic review and meta-analysis

Chen

Huang

et al. 2020

PLoS ONE

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Background The incidence of a positive microscopic ductal margin (R1) after surgical resection for perihilar cholangiocarcinoma (pCCA) remains high, but the beneficial of additional resection has not been confirmed by any meta-analysis and randomized clinical trials (RCT), which also increased the risk of morbidity and mortality. Hence, a systematic review is warranted to evaluate the clinical value of additional resection of intraoperative R1 for pCCA. Methods Eligible studies were searched by PubMed, MedLine, Embase, the Cochrane Library, Web of Science, from Jan.1 st 2000 to Nov.30 th 2019, evaluating the 1-, 3-, and 5-year overall survival (OS) rates of additional resection of intraoperative pathologic R1 for pCCA. Odds ratio (OR) with 95% confidence interval (CI) was used to determine the effect size by a randomized-effect model. Results Eight studies were enrolled in this meta-analysis, including 179 patients in the secondary R0 group, 843 patients in the primary R0 group and 253 patients in the R1 group. The pooled OR for the 1-, 3-, and 5-year OS rate between secondary R0 group and primary R0 group were 1.03(95%CI 0.64~1.67, P = 0.90), 0.92(95%CI 0.52~1.64, P = 0.78), and 0.83(95%CI 0.37~1.84, P = 0.65), respectively. The pooled OR for the 1-, 3-, and 5-year OS rate between secondary R0 group and R1 group were 2.14(95%CI 1.31~3.50, P = 0.002), 2.58 (95%CI 1.28~5.21, P = 0.008), and 3.54(95%CI 1.67~7.50, P = 0.001), respectively. However, subgroup analysis of the West showed that the pooled OR for the 1-, and 3-year OS

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“…This concept has been further explored to develop a probe for transurethral treatment of prostate cancer allowing full or focal gland ablation under MR-guidance [247]. The imaging [154,155,189,193,214] LI: Liver [50,70,82,83,101,145,146,159,163,193,196,[215][216][217][218][219] LU: Lung [87,88,99,114,138,144,157,169,190] PA: [86,93,95,137,158,185,[193][194][195] [150][151][152][153]191] Open circles represent explorative (small/few phase I/II) use and solid black circles represent many/large phase I/II trials, retrospective analyses or phase III evidence.…”

Section: Local Heating Techniquesmentioning

confidence: 99%

“…MW ablation was also found to be safe, feasible, prevent hemorrhage and capable of eradicating tumors in treatment of hepatic adenomas [219]. A recent meta-analysis concluded that transarterial chemoembolization is more successful when combined with MWA for unresectable hepatocellular carcinoma with tumor size >5 cm [163].…”

Section: Local Heating Techniquesmentioning

confidence: 99%

Heating technology for malignant tumors: a review

Kok

Cressman

Ceelen

et al. 2020

International Journal of Hyperthermia

261

188

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The therapeutic application of heat is very effective in cancer treatment. Both hyperthermia, i.e., heating to 39-45 C to induce sensitization to radiotherapy and chemotherapy, and thermal ablation, where temperatures beyond 50 C destroy tumor cells directly are frequently applied in the clinic. Achievement of an effective treatment requires high quality heating equipment, precise thermal dosimetry, and adequate quality assurance. Several types of devices, antennas and heating or power delivery systems have been proposed and developed in recent decades. These vary considerably in technique, heating depth, ability to focus, and in the size of the heating focus. Clinically used heating techniques involve electromagnetic and ultrasonic heating, hyperthermic perfusion and conductive heating. Depending on clinical objectives and available technology, thermal therapies can be subdivided into three broad categories: local, locoregional, or whole body heating. Clinically used local heating techniques include interstitial hyperthermia and ablation, high intensity focused ultrasound (HIFU), scanned focused ultrasound (SFUS), electroporation, nanoparticle heating, intraluminal heating and superficial heating. Locoregional heating techniques include phased array systems, capacitive systems and isolated perfusion. Whole body techniques focus on prevention of heat loss supplemented with energy deposition in the body, e.g., by infrared radiation. This review presents an overview of clinical hyperthermia and ablation devices used for local, locoregional, and whole body therapy. Proven and experimental clinical applications of thermal ablation and hyperthermia are listed. Methods for temperature measurement and the role of treatment planning to control treatments are discussed briefly, as well as future perspectives for heating technology for the treatment of tumors.

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The efficacy of transarterial chemoembolization combined with microwave ablation for unresectable hepatocellular carcinoma: a systematic review and meta-analysis

Cited by 22 publications

References 46 publications

Syntheses, X-ray Crystal Structures, Photoluminescence Properties, Antimicrobial Activities and Hirshfeld Surface of Two New Cd(II) Azide/Thiocyanate Linked Coordination Polymers

Syntheses, X-ray Crystal Structures, Photoluminescence Properties, Antimicrobial Activities and Hirshfeld Surface of Two New Cd(II) Azide/Thiocyanate Linked Coordination Polymers

Does additional resection of a positive microscopic ductal margin benefit patients with perihilar cholangiocarcinoma: A systematic review and meta-analysis

Heating technology for malignant tumors: a review

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