The efficacy of steroids for postoperative persistent inflammatory reaction in a patient with barium peritonitis: A case report

Abstract

HighlightsResidual barium in intraperitoneal cavity causes persistent inflammatory reaction.Steroids are effective for persistent inflammation caused by residual barium.If infectious or other inflammation origins exist, steroids should be avoided.

Perforation of barium sulfate enterography in an infant: A case report

“…[11] Incomplete removal of barium from the abdominal cavity may result in a persistent inflammatory response that is unresponsive to antibiotic treatment, and the use of steroids should be considered. Kojima et al [17] recommended the use of methylprednisolone 500 mg/d for 3 days, followed by gradual tapering of the dosage, which has been effective in controlling inflammatory responses caused by residual barium; however, the specific type of steroids and dosage is not yet certain, and it is important to rule out the presence of a potential source of infection.…”

Barium-induced toxic anterior segment syndrome

“…2 Nevertheless, problems can arise if barium passes through a perforation of the gastro-intestine to induce severe peritonitis. 3,4 It has also been implicated in lung fibrosis. 5 Previously, an outbreak of sterile anterior segment inflammation following cataract surgery was reported to be caused by barium.…”

“…European Journal of Ophthalmology 33 (3) experiments have shown that insoluble barium sulfate attracts leukocytes, causing iritis and corneal opacification followed by the encapsulation of barium sulfate crystals along with fibrin and corneal endothelial cells. 10 We do not yet know how barium apparently elicits a toxic response in the eye, and wonder if the patient described here might have a heightened sensitivity to barium.…”