The efficacy of sodium valproate and a MRA finding in confusional migraine

Fujita, Mitsue; Fujiwara, Junko; Maki, Takako; Shigeta, Midori; Shibasaki, Kayoko; Takahashi, Nobuyuki; Takahashi, Masahide

doi:10.1016/j.braindev.2006.08.001

Cited by 24 publications

(26 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As in the literature the confusional state usually lasted for several hours (3,12). Also in accordance with the literature (10,12), recurring confusional episodes were observed in several of our patients (n=7). In contrast to some reports agitation (3) and amnesia (4, 11, 13) were not major symptoms in most of our patients.…”

Section: Discussionsupporting

confidence: 74%

Confusional migraine is an adult as well as a childhood disease

et al. 2010

View full text Add to dashboard Cite

Background: Acute confusional migraine (ACM) is considered a rare migraine variant primarily seen in children and adolescents. Patients and Methods: We present a series of eight adults and two adolescents suffering from migraine attacks associated with transient confusional states. Results: Eight patients reported two or more such attacks. One of them reported mild head trauma in the past. One patient reported mild head trauma as a possible trigger. Further investigations were unremarkable in all patients and did not suggest underlying structural abnormalities, epilepsy or cerebrovascular disease. In none of these patients did we find another cause to explain the observed phenomenon. Conclusions: Based on this series of patients, we suggest expanding the concept of confusional migraine from the paediatric population to adults. The temporal course of the confusion as well as the association with visual and other aura symptoms suggest cortical spreading depression as the underlying pathophysiology.

show abstract

Section: Discussionsupporting

confidence: 74%

Confusional migraine is an adult as well as a childhood disease

et al. 2010

View full text Add to dashboard Cite

show abstract

“…It should be noted that her left hemisphere appeared to be more affected, in concordance with former individual case reports showing evidence of left circulation involvement. 6,13 After the administration of VPA, our patient's symptoms resolved quickly and did not recur. A repeat EEG a few weeks after the attack was normal.…”

Section: Discussionmentioning

confidence: 68%

“…12 Magnetic resonance angiography in the case of a 10-year-old girl showed narrowing of the left middle and posterior cerebral artery during the ACM attack. 6 Moreover, a 7-year-old boy showed decreased cerebral blood flow in the left posterior splenium region on computed tomography with N-isopropyl[ 123 I]-piodoamphetamine (IMP-SPECT) performed during the attack. 13 It is interesting to note that our patient's EEG revealed more severe involvement of the left hemisphere.…”

Section: Discussionmentioning

confidence: 99%

“…A 10-year-old girl with recurrent ACM responded to VPA as preventive treatment of further attacks. 6 The other report pertained to cases of 2 patients with ACM that responded to prochlorperazine. 17 VPA has also been shown to be effective in an adult patient with cyclic vomiting, which supports its use for migraine equivalents.…”

Section: Discussionmentioning

confidence: 99%

“…5 It was also reported to prevent recurrent ACM attacks in a 10-year-old girl. 6 We describe here the case of a teenaged girl whose symptoms resolved after intravenous administration of VPA during an ACM attack.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Acute Confusional Migraine in an Adolescent: Response to Intravenous Valproate

Avraham¹,

Har-Gil²,

Watemberg³

2010

Pediatrics

View full text Add to dashboard Cite

Acute confusional migraine (ACM) is a dramatic, rare manifestation of migraine described mostly for children and adolescents. There are few data on the treatment of an ACM attack. Prochlorperazine has been suggested as an effective drug. The authors of some reports have suggested that valproic acid may play a role in the prevention of ACM and as treatment for acute migraine headache in the adult population. However, this medication has not been reported as first-line, acute therapy for ACM. We report here the case of a 12-year-old girl who presented with an ACM attack that resolved rapidly after intravenous administration of valproic acid.

show abstract

Headache, epilepsy and photosensitivity: how are they connected?

et al. 2010

View full text Add to dashboard Cite

Although headache and epilepsy have often been associated, the precise electroclinical and pathophysiological interaction between these disorders and in particular its relations with photosensitivity is as yet to be fully understood in adults or children. The association between headache and epilepsy commonly occurs in all types of epilepsy and not only in occipital epilepsy. Generally, peri-ictal headache is often neglected, regardless of its severity, because patients are more concerned about their seizures. Altered cerebral cortex excitability may be the link between these two conditions and photosensitivity shows this. The physician should bear this association in mind when dealing with epileptic and migraine patients so as to be able to offer such patients an accurate diagnosis and appropriate treatment; this should be borne in mind when declaring epileptic patients ‘seizure free’. To date neither the International Headache Society nor the International League against Epilepsy mention that headache/migraine may, on occasion, be the sole ictal epileptic manifestation. Lastly, studies designed to investigate the triggering role of photosensitivity in both headache and epilepsy are warranted.

show abstract

The efficacy of sodium valproate and a MRA finding in confusional migraine

Cited by 24 publications

References 9 publications

Confusional migraine is an adult as well as a childhood disease

Confusional migraine is an adult as well as a childhood disease

Acute Confusional Migraine in an Adolescent: Response to Intravenous Valproate

Headache, epilepsy and photosensitivity: how are they connected?

Contact Info

Product

Resources

About