The efficacy of quantitative gait analysis by the GAITRite system in evaluation of parkinsonian bradykinesia

Chien, Shih Lin; Lin, Shinn Zong; Liang, Chung Chao; Soong, Yi Sheng; Lin, Sheng Huang; Hsin, Yu Loong; Lee, Chi Wei; Chen, Shin-Yuan

doi:10.1016/j.parkreldis.2006.04.004

Cited by 75 publications

(46 citation statements)

References 23 publications

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“…Conversely, the results of our study demonstrated that early moderate PD patients showed a reduction of spatiotemporal gait parameters (speed and cadence), which was confirmed by specific sub-item analysis. Loss of balance, short stride and slowness have been found to be the most prevalent clinical features in PD, after exclusively parkinsonian signs (Morris et al, 1994;Morris et al, 1998;Chien et al, 2006;Sofuwa et al, 2005). Early PD gait may have different characteristics compared with other PD phases.…”

Section: Discussionmentioning

confidence: 99%

Gait analysis and clinical correlations in early Parkinson�s disease

Pistacchi¹

2017

179

106

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SummaryThe aim of our study was to identify and quantify spatiotemporal and kinematic gait parameters obtained by 3D gait analysis (GA) in a group of Parkinson's disease (PD) patients compared with healthy subjects in order to investigate whether early PD patients could present an abnormal gait pattern. Forty-four patients affected by early-stage PD compared with a control group were analyzed. All participants were evaluated with 3D GA in the gait laboratory. The greatest significance in temporal parameters was found in cadence (102.46 ± 13.17 steps/min in parkinsonian patients vs 113.84 ± 4.30 steps/min in control subjects), followed by stride duration (1.19 ± 0.18 seconds right limb and 1.19 ± 0.19 seconds left limb in PD patients vs 0.426 ± 0.16 seconds right limb and 0.429 ± 0.23 seconds left limb in normal subjects) and stance duration. Marked differences were also found in the swing phase and in swing duration (p<0.05), while the stance phase was not significantly different in patients compared with healthy subjects. A statistically different velocity in PD patients (0.082 ± 0.29 m/s) vs healthy subjects (1.33 ± 0.06 m/s) was shown by spatial parameter analysis.Step width, stride length and swing velocity were highly significant parameters, as was average velocity. Our study highlighted some distinguishing characteristics of gait in early PD. Ambulation disorders may be present in the early stage of PD and their detection allows for early medical treatment and possible rehabilitation.

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Section: Discussionmentioning

confidence: 99%

Gait analysis and clinical correlations in early Parkinson�s disease

Pistacchi¹

2017

179

106

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“…These were the items 3.10 (gait) and 3.11 (gait freezing) of the MDS-UPDRS [14], TMT gait [8], 6 min-walking distance [6], 10 mwalk test [9], StandeWalkeSit test [5], Timed up and Go test [7,10], Dynamic Gait Index [7] and FOG-score [11]. All items of these instruments were analyzed in order to select those felt the most relevant to elicit PD-related gait disturbances and to reflect the spectrum of gait in the patients' habitual environment.…”

Section: Construction Of the Dypagsmentioning

confidence: 99%

Construction and validation of the Dynamic Parkinson Gait Scale (DYPAGS)

Crémers

Delvaux

et al. 2012

Parkinsonism & Related Disorders

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a b s t r a c tThe dynamic evaluation of Parkinson's disease (PD)-related episodic gait disturbances in routine is challenging. Therefore, the aim of our study was to assess the reliability/validity of the Dynamic Parkinson Gait Scale (DYPAGS) composed of eight relevant items for the objective quantification of PD gait features: walking forwards/backwards/with dual-task, turning to both sides, imaginary obstacle avoidance with both legs and passing through narrow spaces. The scale was validated on thirty-five patients with mild to severe parkinsonism in their habitual "on-state". A shorter 6 item-version was designed on the basis of a principal component analysis. No significant floor/ceiling effect was detected. The internal consistency was excellent. The levels of interrater agreement, precision and minimal detectable change were adequate. The criterion-related validity was demonstrated by strong correlations with the DYPAGS scores and those at the gait subscales of the Tinetti Mobility Test and MDS-UPDRS. The construct validity was assessed by moderate-strong correlations with the Freezing of Gait Questionnaire, mobility index of the PD Questionnaire (PDQ-39), disease duration and levodopa equivalent daily doses. Statistical analyses using the coefficient of determination showed that both DYPGAS versions were superior to the other instruments to identify patients with gait disturbances with poorer response to dopaminergic treatment. Full and short DYPAGS are reliable instruments for the quantification of "on" PD-related episodic gait disturbances. The full version is sensitive to detect subtle disturbances in mild parkinsonism. The shorter one is easily administered and reliably quantifies gait disturbances in moderate to severe parkinsonism. We recommend their use for research and clinical practice.

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“…No differences between sides were found (p > 0.069), thus left-sided data only were included in all analyses. The GAITRite 1 has demonstrated excellent test-retest reliability in older adults [27], is sensitive to changes in gait parameters in people with PD [28], and has been used as a gold standard comparator when investigating gait under dual task conditions in people with PD [29].…”

Section: Gait Measurementmentioning

confidence: 99%