The Efficacy of Nonpharmacological Treatment for Dementia-related Apathy

Ferrero-Arias, J.; Goñi-Imizcoz, Miguel; González-Bernal, Jerónimo J.; Lara-Ortega, Fernando; Silva-González, Álvaro Da; Díez-Lopez, Mateo

doi:10.1097/wad.0b013e3182087dbc

Cited by 69 publications

(68 citation statements)

References 43 publications

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“…), the Dementia Apathy Interview and Rating (DAIR) scale (Ferrero‐Arias et al . ), the Inventory to Assess Communication, Emotional Expression and Activity in Dementia (ICEA‐D) (Fischer‐Terworth & Probst ) and the Passivity in Dementia Scale (PDS) (Kolanowski et al . , ).…”

Section: Resultsmentioning

confidence: 99%

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Quantitative systematic review of the effects of non‐pharmacological interventions on reducing apathy in persons with dementia

Goris

Ansel

Schutte

2016

Journal of Advanced Nursing

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Study results demonstrate promise for the use of non-pharmacological interventions, particularly music-based interventions, in reducing apathy levels in individuals with dementia. Intervening to reduce apathy may have a positive clinical impact and healthcare providers should be encouraged to incorporate positive sources of interest and intellectual stimulation into care. However, future research is needed to examine the aetiologic mechanism and predictors of apathy, to improve evidence-based interventions and specificity and to optimize dosage and timing of non-pharmacological interventions across the disease trajectory.

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Section: Resultsmentioning

confidence: 99%

“…Ferrero‐Arias et al . () intervened using a combination music, art, psychomotor activity and mime intervention. Niu et al .…”

Section: Resultsmentioning

confidence: 99%

Quantitative systematic review of the effects of non‐pharmacological interventions on reducing apathy in persons with dementia

Goris

Ansel

Schutte

2016

Journal of Advanced Nursing

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“…They easily descend into a downward spiral of lack of activity, with those affected responding poorly to rehabilitation, due to absent motivation (Galynker et al, 1997). According to Ferrero-Arias et al (2011), a structured occupational therapeutic intervention for even a short period of time improves apathy in dementia patients and is much more beneficial than free use of the same amount of time by the patients in a nonstructured environment, but the effect is only useful in patient with mild or moderate dementia, and the effect in patients with severe apathy is even less important. Brodaty and Burns (2012) performed a systematic review on nonpharmacological intervention studies with outcomes relevant to apathy in dementia.…”

Section: Managementmentioning

confidence: 99%

Apathy and Dementia. Nosology, Assessment and Management

Cipriani¹,

Lucetti²,

Danti³

et al. 2014

Journal of Nervous &Amp; Mental Disease

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Apathy, characterized by lack of motivation and loss of initiative, is a non-cognitive symptom that affects a high proportion, but not all, of patients with all forms of dementia. To explore the phenomenon of apathy in people with dementia, we searched the PubMed and Google Scholar electronic databases for original research and review articles on apathetic behaviors in patients with dementia using the search terms "apathy, behavioral and psychological symptoms, dementia, Alzheimer's disease, Frontotemporal dementia, Dementia associated with Parkinson's disease, Huntington's disease, Vascular dementia". Some nosological aspects, neurobiological basis, and assessment of, as well as, potential benefits of non-pharmacologic and pharmacologic interventions for apathy in dementia are discussed. Greater understanding of apathy will improve the identification, intervention, and treatment of this ubiquitous and pernicious syndrome.

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“…Introducing old hobbies and games was successful in reducing disinhibition and inappropriate behaviors in FTD [69]. An apathy trial showed structured occupational therapy activities were more effective than “free time” in mixed group of AD, DLB, and vascular dementia patients, and music was felt to be most helpful [70]. A small but significant improvement in behavioral symptoms has been reported in a meta-analysis of occupational therapy trials using sensory stimulation [71].…”

Section: Assessmentmentioning

confidence: 99%

Non-pharmacological Management of Behavioral Symptoms in Frontotemporal and Other Dementias

Barton

Ketelle

Merrilees

et al. 2016

Curr Neurol Neurosci Rep

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Worldwide prevalence of dementia is predicted to double every 20 years. The most common cause in individuals over 65 is Alzheimer's disease (AD), but in those under 65, frontotemporal dementia (FTD) is as frequent. The physical and cognitive decline that characterizes these diseases is commonly accompanied by troublesome behavioral symptoms. These behavioral symptoms contribute to significant morbidity and mortality among both patients and caregivers. Medications have been largely ineffective in managing these symptoms and carry significant adverse effects. Non-pharmacological interventions have been recommended to precede the utilization of pharmacological treatments. This article reviews the research about these interventions with special attention to the variations by etiology, especially FTD. The authors offer recommendations for improving utilization of these strategies and future research recommendations.

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The Efficacy of Nonpharmacological Treatment for Dementia-related Apathy

Abstract: A structured, nonpharmacological, short-term occupational therapy intervention is more useful than activities of the patients' own choice for improving apathy in patients with mild or moderate dementia.

Cited by 69 publications

References 43 publications

Quantitative systematic review of the effects of non‐pharmacological interventions on reducing apathy in persons with dementia

Quantitative systematic review of the effects of non‐pharmacological interventions on reducing apathy in persons with dementia

Apathy and Dementia. Nosology, Assessment and Management

Non-pharmacological Management of Behavioral Symptoms in Frontotemporal and Other Dementias

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