The efficacy of “IOL-Vip Revolution” telescopic intraocular lens in age-related macular degeneration cases with senile cataract

Abstract

Purpose: To evaluate the efficacy of the IOL-Vip Revolution telescopic intraocular lens in age-related macular degeneration patients. Methods: A total of 13 eyes of 12 age-related macular degeneration patients with senile cataract were enrolled. Selection of the patients was done by means of a low vision diagnostic and rehabilitative program (IOL-Vip software) that evaluates residual visual function. After standard phacoemulsification surgery, the incision site was enlarged and the IOL-Vip Revolution system was implanted in the capsular bag. The outcome measures were best corrected visual acuity, contrast sensitivity, anterior chamber depth, endothelial cell density, central corneal thickness, and quality-of-life questionnaire. Results: The mean age of the subjects was 72.3 ± 8.5 years. The mean positive power of the intraocular lens was 59 ± 2 D and the negative intraocular lens power was standard (–46 D). Pre- and postoperative best corrected visual acuity were 1.08 ± 0.14 and 0.81 ± 0.16 logMAR in the operated eye and 1.13 ± 0.36 and 1.01 ± 0.40 logMAR in the unoperated eye, respectively. The best corrected visual acuity was increased significantly in both operated and unoperated eyes (p = 0.005 and 0.021, respectively). Quality of life and anterior chamber depth increased significantly (p = 0.018 and 0.008, respectively), while endothelial cell density decreased (p = 0.002). No significant differences were detected in central corneal thickness or contrast sensitivity (p = 0.133 and 0.684, respectively). Conclusion: The results showed that IOL-Vip Revolution telescopic intraocular lens is a promising treatment option in age-related macular degeneration patients. The rehabilitation program may have an important role in the restored clinical results, which also provided visual improvement in the unoperated eyes.

Intraocular vision-improving devices in age-related macular degeneration

“…A new study done by 2019 showed that 12 AMD patients with mean age 72.3 were enrolled, and BCVA pre-and post-operation were 1.08±0.14 and 0.81±0.16 log MAR and statistically significant between the difference (P=0.05) (25). Another noncomparative interventional case series (26) depicts the same improvements (the difference was 0.69 Log MAR), and the main best-corrected clinical gain was 44%.…”

“…In one study, they do the preoperative iridotomy in all other cases after noticing 3 of the first 5 cases developed a pupillary block with IOP increased (24). Although 1 article done by Dag et al (25) found that ACD was deeper post-operation from 2.7±0.3 to 3.1±0.7, the mean endothelium cell count was still significantly decreased postoperatively from 2,437±398 to 1,849±376, but lack of further information about the percentage among the subjects. Another study proved that endothelium cell loss appeared in 11.1% of subjects and 5.2% from 12 to 18 months (26).…”

“…Another one is a high biconvex IOL (about +55 D) in the anterior chamber as an objective that can further modify the image. A new model called the IOL-VIP Revolution has also been developed since April 2012, implanted in the capsular bag, unlike the classic form (22). Both IOLs are made of polymethyl methacrylate and can filter the ultraviolet light.…”

“…Meanwhile, it can also be used for training the PRL before and after the surgery. One study shows that the IOL-VIP ® software would recognize more than 66% of patients whose PRL may too far from the fovea and/or not responding adequately to pre-surgical training ahead of the surgery so that none of the articles we found had reported an implantation removal (23) There are 5 articles fitting into the evaluation of the efficacy and safety of IOL-VIP, and 107 patients in total participated in observational studies without any controls (22)(23)(24)(25)(26)(27). Except for 1 article mainly discussed the IOL-VIP ® software (23), others fit into the evaluation of the efficacy and safety of IOL-VIP.…”

Effect of cataract surgery on quality of life for patients with severe vision impairment due to age-related macular degeneration

“…A recent study by Dag et al reported using a telescopic intraocular lens in patients with advanced AMD. They observed that the parameter for difficulty with activities showed improvement (21).…”