The Efficacy of Immediate Implantation of Macroporous Poly(N-[2-Hydroxypropyl]-Methacrylamide) Hydrogel after Laceration Spinal Cord Injury in Young Rats
Abstract:Spinal cord regeneration after mechanical injury is one of the most difficult biomedical problems. This article evaluates the effect of poly(N-[2-hydroxypropyl]-methacrylamide) hydrogel (PHPMA-hydrogel) on spinal cord regeneration in young rats after lateral spinal cord hemi-excision (laceration) at the level of segments T 12 -T 13 (TrGel group). The locomotor function score (FS) and the paretic hindlimb spasticity score (SS) were assessed according to Basso-Beattie-Bresnahan (BBB) and Ashworth scales, respect… Show more
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