The Efficacy of Imiquimod-Induced Psoriasis Model on Murine Cells
Tony Joseph,
Mark Genkin,
Alexander Genkin
et al.
Abstract:Keratinocytes are an essential component of the epidermis that undergoes constant proliferation and differentiation. However, the dysregulation of keratinocyte differentiation has been implicated in various skin disorders such as psoriasis. Imiquimod, otherwise known as IMQ, is a topical immunomodulator often used to induce psoriasis-like lesions in murine models for research purposes. This study focuses on the efficacy of using IMQ to induce a psoriasis-like model on murine skin cells by analyzing single-cell… Show more
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