The efficacy of double reading mammograms in breast screening

Anderson, Elaine; Muir, B. B.; Walsh, J.S.; Kirkpatrick, A. E.

doi:10.1016/s0009-9260(05)81850-1

Cited by 126 publications

(55 citation statements)

References 8 publications

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“…As reported before, semiautomated software volume measurement of pulmonary nodules is highly repeatable ( 30 ). This also explains why the 2.7% increase in our study is much lower than the 6%-15% observed for breast cancer screening (4)(5)(6)(7)(8)(9)(10)(11)(12). In breast cancer screening, lesion identifi cation is relatively diffi cult due to the small difference in density between the lesion and the surrounding normal breast tissue at mammography.…”

Section: Thoracic Imaging: Consensus Double Reading In Ct Lung Cancersupporting

confidence: 67%

“…Several studies have investigated the benefi t of double reading in breast cancer screening and have shown that double reading increased the cancer detection rate by 6%-15% compared with single reading (4)(5)(6)(7)(8)(9)(10)(11)(12). Taking the costs of double reading into account, double reading also appeared to be more cost effective than a single reading policy ( 13,14 ).…”

Section: Study Groupmentioning

confidence: 99%

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No Benefit for Consensus Double Reading at Baseline Screening for Lung Cancer with the Use of Semiautomated Volumetry Software

Wang¹,

Klaveren²,

Bock³

et al. 2012

Radiology

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Purpose:To retrospectively evaluate the performance of consensus double reading compared with single reading at baseline screening of a lung cancer computed tomography (CT) screening trial. Materials and Methods:The study was approved by the Dutch Minister of Health and ethical committees. Written informed consent was obtained from all participants. The benefi t of consensus double reading was expressed by the percentage change in cancer detection rate, recall rate, number of additional nodules detected, and change in sensitivity and specifi city in 7557 participants. The reference standard was a retrospective analysis of the serial CT scans performed in participants diagnosed with lung cancer during a 2-year period after baseline. Semiautomated volumetric software was used for nodule evaluation. McNemar tests were performed to test statistical signifi cance. In addition, sensitivity, specifi city, positive predictive value (PPV), and negative predictive value (NPV) were calculated and 95% confi dence intervals (CIs) constructed. Results:Seventy-four cases of lung cancer were qualifi ed as detectable at baseline. Compared with single reading, consensus double reading did not increase the cancer detection rate (2.7%; 95% CI: 2 1.0%, 6.4%; P = .50) or change the recall rate (20.6% vs 20.8%, P = . Conclusion:There is no statistically signifi cant benefi t for consensus double reading at baseline screening for lung cancer with the use of a nodule management strategy based solely on semiautomated volumetry.

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Section: Thoracic Imaging: Consensus Double Reading In Ct Lung Cancersupporting

confidence: 67%

Section: Study Groupmentioning

confidence: 99%

No Benefit for Consensus Double Reading at Baseline Screening for Lung Cancer with the Use of Semiautomated Volumetry Software

Wang¹,

Klaveren²,

Bock³

et al. 2012

Radiology

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show abstract

“…8 The study was retrospective and non-blinded, where the radiologists were first or second based only on who was available to read at the time. The relative number of first and second readings for the three available radiologists was significantly diVerent ( 2 test: p<0.0001).…”

Section: Discussionmentioning

confidence: 99%

“…This provided papers by Thurfjell, 4 Deans, 6 Warren, 7 and Anderson. 8 Examination of the references in these articles led to the Antinnen 5 and Ciatto 9 papers. The Beam and Sullivan 1 letter was a response to the Thurfjell paper.…”

Section: Methodsmentioning

confidence: 99%

Methodological issues in mammography double reading studies

1998

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Objectives-An examination of the methods used in assessing cancer detection rates in double reading studies to obtain a clear interpretation of the disparate results from diVering studies. Setting-National breast screening programmes. Methods-Critical appraisal of methodologies used in the comparison of cancer detection rates with single or double reading. Results-The reported improvement in cancer detection rate with double reading varies greatly between studies, depending upon whether the study is blinded and the statistic used. A method of calculating the increase in cancer detection rate due to a second reader is proposed. (J Med Screen 1998;5:202-206)

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“…Lezyonun küçük çapta olması veya memenin yoğun yapıda olması, ayrıca memede silikonlu bir meme büyütme ameliyatı yapılmış olması gibi nedenlerle mamografinin hassasiyeti azalmaktadır (16,(21)(22)(23). Mamografi tekniğindeki gelişmeler saptanamayan lezyonların oranını azaltmaktadır.…”

Section: Görüntüleme Yöntemleriunclassified

Occult Breast Cancer

Kebudi¹

2013

J Breasth Health

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Breast carcinoma is the most common malignancy in women after skin cancer and, after lung cancer, the most frequent cause of cancer death in females. With advances in screening over the past 25 years, fewer than 10% of patients will present with metastatic breast carcinoma at the time of diagnosis. Occult breast carcinoma presenting axillary metastases is uncommon and accounts for less than 1% of newly diagnosed breast carcinoma. However, it continues to be a challenging diagnostic and therapeutic problem. In this review, the current approach to diagnosis and treatment of occult breast cancer is discussed. Okult primer meme kanserleri (OMK), T0N1 (evre II) olarak sınıf-landırılmaktadır. Aksiller metastazı olan OMK insidansı düşük-tür. Mamografi öncesi döneme ait üç geniş seride, bu oran tüm meme kanserleri içinde %0,30-1 (2-4) iken, mamografi dönemin-de dört geniş seride bu oran %0,34-0,88 olarak bulunmuştur (5-8) (Tablo 1).Mamografi, ultrasonografi (US) ve Manyetik Rezonanstaki (MR) gelişmelerle birlikte aksiller metastazlı OMK tanısında azalma söz konusudur. Curie Enstitüsü'nde 1960-1997 yılları arasında 59 hasta tedavi edilmiştir (9). Hastalarda medyan yaş 57 (36-79) idi. Otuz beş hasta (%58) postmenopozal dönemde ve iki hasta hormon replasman tedavisi görmekteydi. On beş hastada (%25) meme kanseri aile öyküsü saptandı. Ayrıca diğer çalışmalarda da, bu hasta grubunda ailesel meme kanseri öyküsü yüksek oranda bulunmuştur (6-8). Yirmi sekiz hastada (%47,5) sol aksiller nodlar ve 31 hastada da (%52,5) sağ aksiller nodlar ön plandaydı. TanıKlinik Muayene: OMK tanılı kadınların yaş ortalaması 45-55 arasıdır (10). Lenf nodlarının ortalama çapını Haagensen ve ekibi (11) ile Andrade ve ekibi (12) 4,7 cm, Curie Enstitüsü ise 3 cm olarak vermiştir (13). Nadiren, karşı memede kanser hikayesi olan hastalarda aksiller metastaz görülebilir (14,15). Bu durumda aksilladaki tutulumun nedeninin karşı taraftaki meme kanserinden mi, yoksa aynı taraftaki memedeki yeni, okult bir kanserden mi olduğunu söylemek zordur.Büyümüş aksiller lenf nodları genellikle selimdir, %70 oranında nonspesifik inflamatuvar veya hiperplastik değişikliklere bağlı, %7 oranında da granülomlara bağlı olarak gelişmektedir (16,17). Geriye kalan olgularda malign bir neden vardır. Kadınlarda en sık primer kanser, memenin adenokarsinomudur. Lenfoma ve metastatik kanserler de diğer sebeplerdir. Cilt melanomu, tiroid, akciğer, over, gastrointestinal ve böbrek hücreli kanserler, prostat kanseri meme bölgesine metastaz yapan kanserler olarak sayılabilir (18)(19)(20).Aksiller adenopatisi olan bir kadında tanı amacıyla yapılacak ilk iş, dikkatli bir anamnez alma ve iyi bir fizik muayenedir. Örneğin diğer lenf nodu bulunan bölgelerde yaygın lenfadenopati viral etyoloji

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The efficacy of double reading mammograms in breast screening

Cited by 126 publications

References 8 publications

No Benefit for Consensus Double Reading at Baseline Screening for Lung Cancer with the Use of Semiautomated Volumetry Software

No Benefit for Consensus Double Reading at Baseline Screening for Lung Cancer with the Use of Semiautomated Volumetry Software

Methodological issues in mammography double reading studies

Occult Breast Cancer

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