The efficacy of dexmedetomidine for the prevention of catheter-related bladder discomfort

Lu, Jia; Yang, Xiamin; Zhang, Jie; Huang, Yuelong

doi:10.1097/md.0000000000028217

Cited by 3 publications

(2 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Agents such as dexmedetomidine, ketamine, pregabalin, and tramadol, and intravesical local anesthetic methods are frequently employed. [22,24] However, the risk and benefits are also still unclear. [24] The present study also examined urethral catheter-related pain, and the results show a statistically significant decrease in urethral catheter pain scores at all time points in the RSB group.…”

Section: Discussionmentioning

confidence: 99%

“…[22,24] However, the risk and benefits are also still unclear. [24] The present study also examined urethral catheter-related pain, and the results show a statistically significant decrease in urethral catheter pain scores at all time points in the RSB group. Significantly lower hyoscine n-butylbromide use was also observed in the RSB group, although this was a secondary outcome.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The effect of ultrasound-guided rectus sheath block on postoperative analgesia in robot assisted prostatectomy: A randomized controlled trial

Coşarcan,

Gürkan,

Manici

et al. 2024

Medicine

View full text Add to dashboard Cite

Background: Postoperative pain continues to represent an important problem even after minimally invasive robotic-assisted laparoscopic radical prostatectomy, which results in discomfort in the postoperative period and sometimes prolongs hospital stays. Regional anesthesia and analgesia techniques are used in addition to systemic analgesics with the multimodal approach in postoperative pain management. Ultrasound-guided fascial plane blocks are becoming increasingly important, especially in minimally invasive surgeries. Another important cause of discomfort is urinary catheter pain. The present randomized controlled study investigated the effect of rectus sheath block on postoperative pain and catheter-related bladder discomfort in robotic prostatectomy operations. Methods: This randomized controlled trial was conducted from March to August 2022. Written informed consent was obtained from all participants. Approval for the study was granted by the Clinical Research Ethics Committee. All individuals provided written informed consent, and adults with American Society of Anesthesiologists Physical Condition classification I to III planned for robotic prostatectomy operations under general anesthesia were enrolled. Following computer-assisted randomization, patients were divided into 2 groups, and general anesthesia was induced in all cases. Rectus sheath block was performed under general anesthesia and at the end of the surgery. No fascial plane block was applied to the patients in the non-rectus sheath block (RSB) group. Postoperative pain and urinary catheter pain were assessed using a numerical rating scale. Fentanyl was planned as rescue analgesia in the recovery room. In case of numerical rating scale scores of 4 or more, patients were given 50 µg fentanyl IV, repeated if necessary. The total fentanyl dose administered was recorded in the recovery room. IV morphine patient-controlled analgesia was planned for all patients. All patients’ pain (postoperative pain at surgical site and urethral catheter discomfort) scores and total morphine consumption in the recovery unit and during follow-ups on the ward (3, 6, 12, and 24 hours) in the postoperative period were recorded. Results: Sixty-one patients were evaluated. Total tramadol consumption during follow-up on the ward was significantly higher in the non-RSB group. Fentanyl consumption in the postanesthesia care unit was significantly higher in the non-RSB group. Total morphine consumption was significantly lower in the RSB group at 0 to 12 hours and 12 to 24 hours. Total opioid consumption was 8.81 mg in the RSB group and 19.87 mg in the non-RSB group. A statistically significant decrease in urethral catheter pain was noted in the RSB group at all time points. Conclusion: RSB exhibits effective analgesia by significantly reducing postoperative opioid consumption in robotic prostatectomy operations.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The effect of ultrasound-guided rectus sheath block on postoperative analgesia in robot assisted prostatectomy: A randomized controlled trial

Coşarcan,

Gürkan,

Manici

et al. 2024

Medicine

View full text Add to dashboard Cite

show abstract

Determination of the 90% Effective Dose of Dexmedetomidine for Treating Postoperative Catheter‑related Bladder Discomfort During Recovery: An Open-label, Single-group Study

Ji,

Zheng,

et al. 2024

Journal of PeriAnesthesia Nursing

View full text Add to dashboard Cite

Dose-dependent effect and effective dose of nefopam to prevent catheter-related bladder discomfort in patients undergoing transurethral ureteroscopic lithotripsy: a retrospective case-control observational study

Lee,

Kim,

Lee

et al. 2023

Preprint

View full text Add to dashboard Cite

Background Patients with Foley catheter may experience catheter-related bladder discomfort (CRBD) after surgery. Previous studies have indicated that nefopam can reduce the incidence and severity of CRBD; however, they could not compare dose-dependent effects (20 mg vs. 40 mg). Therefore, we aimed to investigate the dose-dependent effects, effective dose of nefopam for CRBD, and the incidence of side effects. Methods From August 2016 to December 2022, we reviewed the electronic medical records of patients aged 18–70 years with American Society of Anesthesiologists physical status I-III who underwent elective transurethral ureteroscopic lithotripsy under general anesthesia. Patients were either administered premedication to prevent CRBD (intravenous nefopam 20 mg, group N20, or 40 mg, group N40) or not (group C). Results The incidence of CRBD were 85.7% in Group C, 81.3% in Group N20, and 24.3% in Group N40. There was a significant difference in the incidence between the groups (P = 0.0034). As the dose of nefopam increased, the incidence of CRBD decreased linearly, and the difference was statistically significant (P = 0.002). In the trend test, severity also decreased as the dose of nefopam increased, which was statistically significant (P < 0.001). Evaluation of hemodynamic stability during surgery and postoperative nausea and vomiting showed no significant differences among the three groups. Conclusions Nefopam 40 mg reduced both the incidence and severity of CRBD compared to the control group. Trial registration number: ID- KCT0008381 (https://trialsearch.who.int/Trial2.aspx?TrialID=KCT0008381) Date of registration – 2023-04-25

show abstract

The efficacy of dexmedetomidine for the prevention of catheter-related bladder discomfort

Cited by 3 publications

References 19 publications

The effect of ultrasound-guided rectus sheath block on postoperative analgesia in robot assisted prostatectomy: A randomized controlled trial

The effect of ultrasound-guided rectus sheath block on postoperative analgesia in robot assisted prostatectomy: A randomized controlled trial

Determination of the 90% Effective Dose of Dexmedetomidine for Treating Postoperative Catheter‑related Bladder Discomfort During Recovery: An Open-label, Single-group Study

Dose-dependent effect and effective dose of nefopam to prevent catheter-related bladder discomfort in patients undergoing transurethral ureteroscopic lithotripsy: a retrospective case-control observational study

Contact Info

Product

Resources

About