The Efficacy of Amniotic Membrane Stem Cell (AMSC) Metabolite Product and Vitamin E for Wrinkles, Spots, and Pores in Photoaging

Rahmadewi, Rahmadewi; Retha, Retha; Pitasari, Dyah Ayu; Kusumastanto, Vidyani Adiningtyas; Ardhaninggar, Agatha Anindita Ayu; Citrashanty, Irmadita; Sari, Maylita; Umborowati, Menul Ayu; Prakoeswa, Cita Rosita Sigit

doi:10.1155/2020/1584541

Cited by 10 publications

(10 citation statements)

References 18 publications

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“…1 Skin aging in women can affect mood, self-confidence and quality of life. 3 In addition, skin aging in women is associated with decreased dehydroepiandrosterone (DHEA) hormone. It causes the reduction of type I procollagen expression, which then decreases collagen synthesis and accelerates collagen degradation.…”

Section: Discussionmentioning

confidence: 99%

“…Indonesian people are prone to photoaging, as Indonesia is a tropical country with constant sun exposure throughout the year. 3 In Indonesia, chemical peeling has been used as a treatment option for photoaging patients. Glycolic acid peeling was performed on 72 photoaging patients, representing 15.8% of all photoaging patients (455 patients) at Medical Cosmetics Division Dermatology and Venereology Department of Dr. Soetomo General Academic Hospital Surabaya between 2011 and 2013.…”

Section: Introductionmentioning

confidence: 99%

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Chemical Peeling in Skin-Aging Patients: A Retrospective Study

Susanto

Setyaningrum

Mustika

et al. 2023

BIKK

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Background: Skin aging is a degenerative process that involves a decrease in the structure and function of skin cells and theextracellular matrix due to intrinsic and extrinsic factors. Chemical peeling is one of the skin aging treatments that involvesskin ablation using chemical agents. Purpose: To evaluate the profile of skin-aging patients treated with chemical peeling atthe Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Hospital Surabaya from January throughDecember 2019. Methods: The data were obtained from patients’ medical records through a total sampling technique, whichconsisted of age, gender, occupation, history taking, physical examination, diagnosis, therapeutic agents, follow-up frequency,and therapeutic result. Result: The study included 37 patients, the majority of whom were between the ages of 46 and 55(35.1%), female (100%), and private employees (32.4%). In history taking, patients’ main complaint is dull skin (94.6%), withthe risk factor of sun exposure (97.3%) and the history of sunscreen usage (81.1%). Pigmentary changes were found in allpatients (100%). The most common diagnoses are photoaging Glogau II and Glogau III, found in 15 patients (40.5%),respectively. The common priming agents were sunscreen (97.3%), cleanser (94.6%), and 8% glycolic acid (75.7%). Themajority of patients (62.2%) received 20% glycolic acid as a peeling agent and sunscreen (86.5%) as a post-peeling agent.The majority of patients (43.2%) did not follow up. Glogau II photoaging (57.1%) was the main therapeutic result.Conclusion: Proper chemical peeling procedures and patients compliance are important factors to improve therapeuticoutcomes.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Chemical Peeling in Skin-Aging Patients: A Retrospective Study

Susanto

Setyaningrum

Mustika

et al. 2023

BIKK

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“…Their anti-aging potential has been associated with the release of growth factors, angio-modulatory cytokines, anti-bacterial peptides, and anti-inflammatory molecules [ 82 ]. A study showed that a topical application of AMSC metabolic products combined with vitamin E significantly improved wrinkles, ultraviolet spots, and pores in patients with photoaging [ 83 ]. ADSCs have also shown promise for facial skin rejuvenation [ 84 ].…”

Section: Reviewmentioning

confidence: 99%

Clinically Actionable Topical Strategies for Addressing the Hallmarks of Skin Aging: A Primer for Aesthetic Medicine Practitioners

Minoretti,

Emanuele

2024

Cureus

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In this narrative review, we sought to provide a comprehensive overview of the mechanisms underlying cutaneous senescence, framed by the twelve traditional hallmarks of aging. These include genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, impaired macroautophagy, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis. We also examined how topical interventions targeting these hallmarks can be integrated with conventional aesthetic medicine techniques to enhance skin rejuvenation. The potential of combining targeted topical therapies against the aging hallmarks with minimally invasive procedures represents a significant advancement in aesthetic medicine, offering personalized and effective strategies to combat skin aging. The reviewed evidence paves the way for future advancements and underscores the transformative potential of integrating scientifically validated interventions targeted against aging hallmarks into traditional aesthetic practices.

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“…Statically, there is a significant difference (p 0.05) shown in Table 3. In the moisture test for each volunteer gave good results, especially for formula (3), which consists of aloe vera essence of 5 % combined with vitamin E. Due to the increase in hydration of the skin from the coverage of the biocellulose sheet mask and the combined effect of aloe and vitamin E that improves skin elasticity and also provides collagen, preventing wrinkles from taking place [28].…”

Section: Good Antioxidant Testing Greatly Affects the Effect Of Antio...mentioning

confidence: 99%

Formulation of a biocellulose mask containing the essence of Aloe vera (L.) Burm.f combination with vitamin E as anti-aging

Fitri

Syahputra²,

Nasri³

et al. 2022

SR: PS

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Most ageing processes are accelerated due to an increasing amount of endogenic stress from outdoor or indoor activity overload. The essence of aloe vera is formulated in the form of a biocellulose mask. It is one of the solutions to deliver essence within polymeric substances, obtained through the fermentation process with the help of Acetobacter xyllinum. The aim of this study is to enhance anti-ageing activity derived from Aloe vera (L) essence combined with vitamin E, thus in the form of a biocellulose mask that will prolong skin contact and reduce the main cotton sheet mask problem of deforestation, hence its eco-friendly benefit. Material and methods: Twelve volunteers around 25 to 45 years old are subjected to a biocellulose mask containing Aloe vera essence combined with vitamin E for at least 4 weeks to achieve a balanced skin criterion including wrinkles, spots, facial pores, and moisture. Aloe vera and vitamin E constituents within F0; F1, F2; F3, [0%, 0%]; [0%, 1%]; [5%, 0 %] and [5 %, 1 %] as per the following. Results: Results showed that bio-cellulose masks containing 5 % Aloe vera with 1 % of vitamin E essence in F3 provide a beneficial anti-ageing activity rather than other biocellulose mask preparations. Conclusion: Biocellulose mask through the fermentation process can improve skin conditions, the formula combined with the well-known activity of aloe vera as an exfoliating agent and antioxidant vitamin E, it can not only provide skin rejuvenation but also provide anti-ageing activity

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The Efficacy of Amniotic Membrane Stem Cell (AMSC) Metabolite Product and Vitamin E for Wrinkles, Spots, and Pores in Photoaging

Cited by 10 publications

References 18 publications

Chemical Peeling in Skin-Aging Patients: A Retrospective Study

Chemical Peeling in Skin-Aging Patients: A Retrospective Study

Clinically Actionable Topical Strategies for Addressing the Hallmarks of Skin Aging: A Primer for Aesthetic Medicine Practitioners

Formulation of a biocellulose mask containing the essence of Aloe vera (L.) Burm.f combination with vitamin E as anti-aging

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