Neurodermatitis, also known as atopic dermatitis or atopic eczema is the long-term inflammation in the skin. There are many different kinds of therapies without clear conclusions and recommendations as to which therapy is the most effective and safest. This paper aims to compare the effectiveness and safety of four commonly used therapies: steroid therapy, traditional Chinese medicine (TCM), Phototherapy, and habit reversal. The methodology used was through gathering/searching papers with keywords such as, neurodermatitis management, atopic dermatitis, habit reversal, steroid therapy, and comparing the effectiveness and safety of the varying therapies. The results showed us that studies concerning the different therapies should be explored and more therapies need data for us to come to a clear recommendation.