The Efficacy and Mechanism of Kaempferol in Preventing perioperative neurocognitive disorders in the Elderly: Based on Network Pharmacology and Experimental Verification
Enhao Huang,
Huadao LI,
Hanghang Han
et al.
Abstract:Objective:This research, founded on network pharmacology, molecular docking, and experimental validation, seeks to elucidate the probable therapeutic effects of Kaempferol on perioperative neurocognitive disorders,along with its operational mechanism.
Methods:Key target points for the potential preventive effects of Kaempferol (Kae) on perioperative neurocognitive disorders (PND) were discerned through the Geo database and network pharmacology techniques. An animal model was established for PND through laparot… Show more
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