The Effects of Variations in End-Expiratory Inflation Pressure on Cardiorespiratory Function in Normo-, Hypo- And Hypervolaemic Dogs

Sykes, M.K.; Adams, A. P.; Finlay, W.E.I.; McCormick, Patrick W.; Economides, Apollo P.

doi:10.1097/00132586-197204000-00009

Cited by 13 publications

(18 citation statements)

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“…Here the drop in systolic pressure and in pulse pressure was most marked in the CPPV-5 group, but this may be due to the fact that the preanaesthetic blood pressure was slightly higher in this group. These minimal effects on arterial pressure are in accordance with previous studies dealing with the haemodynamic effects of various forms of pressure ventilation (MALONEY et al 1951, OTIS et al 1946, SYKES et al 1970. MORGAN et al (1966) found only about a 10% decrease in stroke volume in dogs using IPPV under conditions similar to those used in the present study, (i.e., with inspiration: expira-tion ratio 1 :2 and peak airway pressures not exceeding 20 cmH,O).…”

Section: Discussionsupporting

confidence: 93%

Effect of Positive Pressure Ventilation on Plasma Catecholamines

Takki

Tammisto

1973

Acta Anaesthesiol Scand

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Changes in plasma catecholamines, blood pressure, heart rate and central venous pressure associated with three different types of positive pressure ventilation (IPPV, CPPV-5 and IPNPV-5) were studied in 2 1 patients who received normoventilation and were anaesthetized using the N,O-0,-relaxant-analgesic technique. Total catecholamines, adrenaline and noradrenaline were determined by the method of VENDSALU (1960).CPPV-5 caused a higher mean peak inspiratory pressure than IPPV or IPNPV-5. Central venous pressure was elevated in all groups during the first 5 min, but fell thereafter to a significantly lower level in the IPNPV-5 group than in the IPPV or CPPV-5 groups. Blood pressure fell in all groups 20 to 30 mmHg under the preanaesthetic level. During the first 5 min, the fall was most pronounced in the CPPV-5 group, but thereafter no significant differences between the groups were found.Plasma catecholamines increased slightly, but statistically insignificantly, in the CPPV-5 group during the whole observation period. The levels of adrenaline and noradrenaline did not change significantly in any of the groups.

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Section: Discussionsupporting

confidence: 93%

Effect of Positive Pressure Ventilation on Plasma Catecholamines

Takki

Tammisto

1973

Acta Anaesthesiol Scand

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“…16 Potential deleterious effects of pre-hospital ETI on survival include increased pre-hospital time, complications of unsuccessful ETI, brain hypoxia due to hyperventilation in head injured patients, and hemodynamic effects of positive pressure ventilation in hypovolemic patients. [17][18][19][20][21][22] We undertook this study to assess the impact of prehospital positive pressure ventilation on hemodynamic physiology in a group of hypovolemic trauma patients with head injuries. Our hypothesis was that pre-hospital ETI worsens survival, and that this effect is mediated by hypotension associated with pre-hospital ETI.…”

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confidence: 99%

Pre-Hospital Endotracheal Intubation and Positive Pressure Ventilation Is Associated with Hypotension and Decreased Survival in Hypovolemic Trauma Patients: An Analysis of the National Trauma Data Bank

Shafi

Gentilello

2005

The Journal of Trauma: Injury, Infection, and Critical Care

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“…The high venous pressure distends the capacitance vessels and reduces the compliance of those vessels. Clinical experience and animal studies (SYKES et al 1970, QVIST et al 1975 suggest that volume replacement counteracts the fall in cardiac index due to PEEP.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Positive End Expiratory Pressure after Three Types of Open Heart Surgery

Harboe¹,

Levang²,

Hysing³

1979

Acta Anaesthesiol Scand

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It has previously been shown that patients who have undergone mitral valve replacement (MVR) tolerate a positive end expiratory pressure (PEEP) of 1.0 kPa better than patients who have had aortic valve replacement (AVR). the difference was explained by the fact that the mitral patients had pre-existing pulmonary vascular disease. In the present study the effect of PEEP up to 2.0 kPa is investigated in three types of operations: aortocoronary bypass graft (ACBG), mitral valve replacement, and aortic valve replacement; there were five patients in each group. We found that our mitral patients tolerated PEEP better than the two other groups, and that tolerance was not correlated to a higher pulmonary vascular resistance, but rather to a higher level of pulmonary capillary wedge pressure. The influence of PEEP varies in different types of patients and the effect is still difficult to predict.

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The Effects of Variations in End-Expiratory Inflation Pressure on Cardiorespiratory Function in Normo-, Hypo- And Hypervolaemic Dogs

Cited by 13 publications

References 0 publications

Effect of Positive Pressure Ventilation on Plasma Catecholamines

Effect of Positive Pressure Ventilation on Plasma Catecholamines

Pre-Hospital Endotracheal Intubation and Positive Pressure Ventilation Is Associated with Hypotension and Decreased Survival in Hypovolemic Trauma Patients: An Analysis of the National Trauma Data Bank

The Effect of Positive End Expiratory Pressure after Three Types of Open Heart Surgery

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