2007
DOI: 10.1016/j.arthro.2007.05.018
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The Effects of Valgus Medial Opening Wedge High Tibial Osteotomy on Articular Cartilage Pressure of the Knee: A Biomechanical Study

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Cited by 300 publications
(288 citation statements)
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“…Indeed, degenerative changes associated with meniscectomies have been linked to increased joint contact stress (hereafter referred to as contact pressure) in the adjacent articular cartilage as measured in vitro [18][19][20][21][22][23][24][25][26][27] . To date, however, experimental models have been primarily conducted under static or quasi-static uniaxial loading conditions 8,[28][29][30][31][32][33] . Given the sensitivity of joint contact pressures to the magnitude and direction of an applied load 34,35 , these models do not accurately capture the physiological effect of meniscal repair or meniscectomy on knee contact mechanics.…”
mentioning
confidence: 99%
“…Indeed, degenerative changes associated with meniscectomies have been linked to increased joint contact stress (hereafter referred to as contact pressure) in the adjacent articular cartilage as measured in vitro [18][19][20][21][22][23][24][25][26][27] . To date, however, experimental models have been primarily conducted under static or quasi-static uniaxial loading conditions 8,[28][29][30][31][32][33] . Given the sensitivity of joint contact pressures to the magnitude and direction of an applied load 34,35 , these models do not accurately capture the physiological effect of meniscal repair or meniscectomy on knee contact mechanics.…”
mentioning
confidence: 99%
“…Sowohl bei In-vitro-Studien an Kniegelenkpräparaten als auch in In-vivo-Studien (instrumentierte Hüftprothe-sen) ließ sich nachweisen, dass der Knorpeldruck im betroffenen Gelenkabschnitt signifikant ansteigt, wenn die mechanische Traglinie aus der Kniemitte nach medial bzw. lateral verschoben wird [2,15]. Achsenfehler im Varus-bzw.…”
Section: Prinzip Der Osteotomieunclassified
“…die Arthroseprogredienz. In Laboruntersuchungen ließ sich jedoch auch eindeutig nachweisen, dass eine Korrektur des Achsenfehlers eine Entlastung des Knorpels bewirkt und dass das Ausmaß der Verschiebung der mechanischen Traglinie direkt mit der Reduktion des Knorpeldruckes korrelierte [2,15]. Klinische Studien haben die positive Entwicklung des Schmerzniveaus und der Belastbarkeit des Kniegelenks bestätigt [8,14,25].…”
Section: Prinzip Der Osteotomieunclassified
“…Postoperative alignment is crucial to the outcome of the procedure [61], with undercorrection leading to poor clinical outcomes [62•] and progression of medial osteoarthritis [63]. While the influence of overcorrection is more controversial [64], it may lead to early failure secondary to lateral compartment overload [65], patellar subluxation, and medial joint opening [66]. CAS systems that accurately provide limb alignment are well established in knee arthroplasty [67] and are easily adapted to osteotomy procedures.…”
Section: High Tibial Osteotomymentioning
confidence: 99%