The Effects of Two Different Doses of Calcium Lactate on Blood pH, Bicarbonate, and Repeated High-Intensity Exercise Performance

Abstract

We investigated the effects of low- and high-dose calcium lactate supplementation on blood pH and bicarbonate (Study A) and on repeated high-intensity performance (Study B). In Study A, 10 young, physically active men (age: 24 ± 2.5 years; weight: 79.2 ± 9.45 kg; height: 1.79 ± 0.06 m) were assigned to acutely receive three different treatments, in a crossover fashion: high-dose calcium lactate (HD: 300 mg · kg(-1) body mass), low-dose calcium lactate (LD: 150 mg · kg(-1) body mass) and placebo (PL). During each visit, participants received one of these treatments and were assessed for blood pH and bicarbonate 0, 60, 90, 120, 150, 180, and 240 min following ingestion. In Study B, 12 young male participants (age: 26 ± 4.5 years; weight: 82.0 ± 11.0 kg; height: 1.81 ± 0.07 m) received the same treatments of Study A. Ninety minutes after ingestion, participants underwent 3 bouts of the upper-body Wingate test and were assessed for blood pH and bicarbonate 0 and 90 min following ingestion and immediately after exercise. In Study A, both HD and LD promoted slight but significant increases in blood bicarbonate (31.47 ± 1.57 and 31.69 ± 1.04 mmol · L(-1, respectively) and pH levels (7.36 ± 0.02 and 7.36 ± 0.01, respectively), with no effect of PL. In Study B, total work done, peak power, mean power output were not affected by treatments. In conclusion, low- and high-dose calcium lactate supplementation induced similar, yet very discrete, increases in blood pH and bicarbonate, which were not sufficiently large to improve repeated high-intensity performance.

Chronic lactate supplementation does not improve blood buffering capacity and repeated high‐intensity exercise

“…Van Montfoort et al (2004) showed a small improvement in exercise tolerance in a continuous run-to-exhaustion protocol lasting~80 s, while Morris et al (2011) showed that acute lactate ingestion improved exercise performance by 17% in a supramaximal exercise tolerance test following four repeated maximal exercise bouts. In contrast to these findings, an investigation from our group did not show any ergogenic effect of acute lactate ingestion on repeated supramaximal exercise, although minor increases in blood bicarbonate were shown (Painelli et al, 2014b). Since the exercise protocol used by Painelli et al (2014b) was highly acidotic and sensitive to detect performance improvements elicited by increased blood buffering capacity (Artioli et al, 2007;Tobias et al, 2013), these results have cast some doubt as to whether lactate is an effective buffering agent.…”

“…In contrast to these findings, an investigation from our group did not show any ergogenic effect of acute lactate ingestion on repeated supramaximal exercise, although minor increases in blood bicarbonate were shown (Painelli et al, 2014b). Since the exercise protocol used by Painelli et al (2014b) was highly acidotic and sensitive to detect performance improvements elicited by increased blood buffering capacity (Artioli et al, 2007;Tobias et al, 2013), these results have cast some doubt as to whether lactate is an effective buffering agent. One possible explanation for the lack of a positive effect with lactate could be related to the use of acute supplementation protocols since their alkalinizing effects are transient, meaning that blood pH and bicarbonate return to baseline levels shortly after ingestion (Painelli et al, 2014b;Siegler et al, 2010).…”

Efeitos da suplementação crônica de lactato de cálcio e bicarbonato de sódio sobre desempenho físico em exercício intermitente de alta intensidade

“…Key words: buffering, wingate upper-body, muscle fatigue and physical performance. Sanguíneas ................................................................................. 40 4.7 Análise Estatística ..................................................................................................... 41 ................................................................................................... 43 6.1 (ARTIOLI et al, 2007;LINDH et al, 2008;SIEGLER e HIRSCHER, 2010 (ARTIOLI, et al, 2007;PAINELLI et al, 2014;TOBIAS et al, 2013 Isso ajuda na manutenção do pH intramuscular e possibilita a manutenção do desempenho no exercício de alta intensidade (HOBSON et al, 2012). processo contrátil e sobre a via glicolítica, levando ao retardo do aparecimento da fadiga (BISHOP et al, 2004).…”

“…Contudo, apenas um estudo apresentou resultados positivos, com uma grande melhora de 25% no desempenho aeróbio (AZEVEDO et al, 2007). No entanto, como há aumento dos níveis de pH (FAHEY et al, 1991;MORRIS, et al, 2011;PAINELLI et al, 2014) e bicarbonato (FAHEY et al, 1991;PAINELLI et al, 2014) (MCNAUGHTON, et al, 1999), pois pode promover um incremento maior no bicarbonato sanguíneo com o maior período de suplementação, mas esse protocolo ainda precisa ser explorado. Os dados estão apresentados como média ± desvio-padrão.…”

“…Trabalhos do nosso grupo confirmam que o protocolo de avaliação adotado induz acentuada acidose metabólica (PAINELLI et al, 2014), sendo sensível às melhoras promovidas pelo uso de substâncias tamponantes (ARTIOLI, et al, 2007;TOBIAS et al, 2013). Foi incluída a recuperação ativa durante o intervalo entre cada série, para evitar o reflexo vagal que gera hipotensão que tipicamente ocorre após um exercício de máxima intensidade do tipo all-out.…”