The Effects of Transfusion on a Neurovascular Unit in an Experiment Using Its Cellular Model
Artem A. Ivkin,
Evgeny Grigoriev,
Andrey V. Morgun
et al.
Abstract:Purpose of the study: to reveal how the transfusion and the refraining from it affects the neuro-vascular unit in the congenital heart defects correction with cardiopulmonary bypass. Materials and methods: in vitro research, we formed a model of a neurovascular unit, which contains neu-rons, astrocytes and endothelial cells. This cellular model was cultivated in hypoxia conditions with the oxygen saturation levels of 1, 2, 3, 4%. In addition, this unit was cultivated with the pa-tient's serum adding i… Show more
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