The effects of three remineralizing agents on regression of white spot lesions in children: A two-week, single-blind, randomized clinical trial

Ebrahimi, Mohsen; Mehrabkhani, Maryam; Ahrari, Farzaneh; Parisay, Iman; Jahantigh, Maliheh

doi:10.4317/jced.53582

Cited by 29 publications

(36 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Enamel remineralization of different calcium-phosphate and uoride delivery systems were assessed with Vyavhare et al, (27) who compared the remineralization potential of uoride, nano-hydroxyapatite, and CPP-ACP and they stated that tested materials had high remineralization potential of uoride. Also, Ebrahimi et al, (28) agreed with the results of multiple studies who proved signi cant reduction of white spot lesions after the use of products containing CPP-ACP or CPP-ACPF. The results of this study agreed with Damyanova et al, (29) who used Clinpro white varnish and TCP and stated that it is effective lessening demineralization within the subsurface layer and in improving the remineralization of surface and subsurface enamel layer.…”

Section: Discussionsupporting

confidence: 78%

Impact of Two Remineralizing Agents on White Spot Lesions

Alagha

2020

Preprint

View full text Add to dashboard Cite

Aim of the study: This study evaluated the impact of two remineralizing agents containing casein phosphopeptideamorphous calcium phosphate (CPPACP), and Tricalcium phosphate (TCP) on white spot lesions. Materials and Methods: A total of ninety freshly extracted upper premolars were divided in three equal groups (30 each). Group A: Control group. Group B: Varnish containing CPP–ACP. Group C: Varnish containing TCP. The teeth were subjected to Diagnodent test after inducing white spot lesions to assess any surface changes present on the teeth. The readings were repeated post demineralization and post-remineralization. Results: Statistically significant difference was present in the mean values between the tested groups. CPP-ACP group recorded higher mean value at demineralization when compared to TCP group. Statistically significant difference (p < 0.0001) was present between the baseline and the demineralization values. CPP-ACP group presented higher remineralization results when compared to TCP group. T-test proved a significant difference between the tested groups. Conclusion: CPP-ACP containing varnish had higher remineralizing effect when compared to TCP containing varnish. Clinical Significance: Recently, the focus of restorative dentistry has been directed toward a conservative approach. Prevention and non-restorative treatment of initial enamel caries is the main concern. Remineralization procedures are the most preferred way of regeneration of lost tooth structure.

show abstract

Section: Discussionsupporting

confidence: 78%

Impact of Two Remineralizing Agents on White Spot Lesions

Alagha

2020

Preprint

View full text Add to dashboard Cite

show abstract

“…In the study of Mohan et al ( 31 ) an increase in Ca/p ratio was observed with the combination of laser irradiation and Remin Pro®. This was attributed to the presence of hydroxyapatite crystals in this topical paste ( 30 ).…”

Section: Discussionmentioning

confidence: 99%

“…Remin Pro® is a water-based cream that contains three components: hydroxyapatite, 1450 ppm of fluoride and xylitol as a sugar substitute with cariostatic properties. It is assumed that the ingredients in this topical agent enhance the potential of remineralization; limit the adhesion of bacterial plaque to enamel and reinforce the tooth against further carious attack ( 30 ). The outcomes of this study are similar to those of Mohan et al ( 31 ) who showed an increase in mineral content when CO2 laser irradiation was done before and after the application of Remin Pro® paste on the enamel surface.…”

Section: Discussionmentioning

confidence: 99%

Evaluation the effect of the diode laser irradiation associated with photoabsorbing cream containing remineralizing agents on microhardness, morphology and the chemical structure of early enamel caries

et al. 2018

Self Cite

View full text Add to dashboard Cite

BackgroundThis study investigated the effects of laser irradiation associated with photo-absorbing agents containing sodium fluoride (NaF), MI paste Plus or Remin Pro® on microhardness and surface structure of white spot lesions (WSLs).Material and MethodsFifty-six premolars were divided into two halves, then immersed in a demineraling solution to induce WSLs. The samples were divided into 8 groups by treatment (n=12) : (1) control, (2) diode laser (810 nm, 500 mW, 90 s), (3) NaF, (4) MI Paste plus, (5) Remin Pro®, (6) NaF + Laser, (7) MI Paste Plus + Laser, (8) Remin Pro® + Laser. Microhardness was measured before and after remineralization treatments. Two samples from each group were selected for SEM analysis.ResultsMicrohardness increased significantly after all treatments with the exception of control, Laser and Remin Pro® groups (p >0.05). ANOVA revealed no significant difference in initial microhardness (P=0.21), whereas a significant difference was noted after treatment (P=0.009). The application of sodium fluoride with or without laser irradiation produced the highest microhardness among the groups (p<0.05). SEM analysis revealed some cracks on lased enamel and non-homogenous coatings of minerals after the use of remineralizing products.ConclusionsThe use of NaF either alone or combined with laser irradiation was the most effecttive strategy for increasing microhardness of WSLs. The application of diode laser through photoabsorbing agents containing sodium fluoride or MI Paste Plus did not produce any additional effects in enhancing remineralization of WSLs, whereas the combined application of diode laser with Remin Pro® was effective. Key words:CPP-ACP, Enamel caries, fluoride, Hydroxyapatite, Low level laser, Microhardness, Remineralization, casein phosphopeptide amorphous calcium phosphate.

show abstract

“…The difference in results may be due to the less use of these products compared to the previous studies. [37][38][39][40] Yet, some studies have found no significant difference between these materials and the saliva group, whether used for prevention or treatment, which seems to be due to short-term use of these materials followed by daily irrigation. 11,21,41 Since the duration of use of the material in this study was increased by five minutes each time, no significant difference was observed compared to the control group.…”

Section: Discussionmentioning

confidence: 99%

The Effect of the Er:YAG Laser and MI Paste Plus on the Treatment of White Spot Lesions

Yassaei

Motallaei²

2020

J Lasers Med Sci

View full text Add to dashboard Cite

Introduction: White spot lesions (WSLs) occurring after orthodontic treatment lead to patient dissatisfaction and aesthetic problems. The role of calcium-phosphate demineralization systems and the Er:YAG laser in the treatment of these lesions has recently been taken into account. This study aimed to investigate the effect of the Er:YAG laser and MI Paste Plus on the treatment of WSLs. Methods: A total of 65 premolars extracted due to orthodontic treatment were studied in this research. To create enamel lesions, the teeth were placed in a demineralizing solution. The teeth were then randomly divided into five groups (n=13) as follows: first group, control; second group, saliva; third group, MI Paste Plus; fourth group, Er:YAG laser; and fifth group, MI Paste Plus together with the Er:YAG laser. The teeth were kept in artificial saliva between treatment processes. Artificial saliva was replaced daily with fresh artificial saliva. The teeth were sectioned longitudinally by a disc from the middle of the exposed enamel and each section was mounted in polyester resin. The surface of the samples was serially polished and the microhardness of the teeth was measured at depths of 0, 50, 100, and 150 µm. Results: The microhardness was significantly higher in the fifth group than other groups at depths of 50 and 150 µm (P<0.005). Using the laser or MI Paste Plus alone did not significantly increase the microhardness. Conclusions: The combined application of the Er:YAG laser and MI Paste Plus is effective in the treatment of WSLs.

show abstract

The effects of three remineralizing agents on regression of white spot lesions in children: A two-week, single-blind, randomized clinical trial

Cited by 29 publications

References 29 publications

Impact of Two Remineralizing Agents on White Spot Lesions

Impact of Two Remineralizing Agents on White Spot Lesions

Evaluation the effect of the diode laser irradiation associated with photoabsorbing cream containing remineralizing agents on microhardness, morphology and the chemical structure of early enamel caries

The Effect of the Er:YAG Laser and MI Paste Plus on the Treatment of White Spot Lesions

Contact Info

Product

Resources

About