Began from the end of 2019, the SARS-CoV-2 outbreaks in Wuhan, China, this unknown virus are first been recognized and it continues to devastate millions worldwide. As more individual has been infected, Covid-19 has been considered an international public health event and research on its pathogenesis and impacts are necessary. Some research has already shown that the virus can also infect multi organs including human gut enterocytes and the respiratory tract and brings both short-term and long-term effects to humans, the more research has shown the varying immediate symptoms of Covid-19 including acute respiratory distress (ARDS), fever, cytokines storm and long-term risk with the impacts on heart, male reproductive system, neurological and psychological health, and other mysterious risks. In this article, multiple journals and review articles have been researched and managed into long-term and short-term sections, the result shows that Covid-19 has significant impacts on humans for both chronical and instant manifestations.