“…[21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39] The main reasons for exclusion were: case reports, reviews, opinion articles, studies concerning treatment in permanent dentition/adult patients, and studies about association between Class III malocclusion and malformation. Six of the studies were performed in the United States, 21,24,25,30,34,39 five in Japan, 28,29,31,33,37 four in Turkey, 22,26,32,38 two in the UK, 23,27 one in Korea, 35 and one in Italy. 36 …”