Abstract:Aim The aim of this study is to investigate the effects of sulforaphane (SFN), which has been shown to protect such organs as the brain, kidneys, liver, and heart against the injury caused by ischemia reperfusion (I-R), on the reperfusion injury in the experimental intestinal I-R model.Material and method The study employed 30 Wistar albino rats, and there were three groups: the control group (n = 10), I-R group (n = 10), and SFN + I-R group (n = 10). The rats in the control group were sacrificed after a 3-h f… Show more
“…Histopathological changes in the jejunum due to IR injury were evaluated according to the grading of Chiu et al 3…”
Section: Measurementsmentioning
confidence: 99%
“…The pathogenesis of ischemia reperfusion (IR) is due to both the depletion of cellular energy sources due to tissue hypoxia during ischemia and, more importantly, to the formation of O2-derived free radicals during reperfusion. The IR process can cause dysfunction and damage not only to the organ in which it is involved but also to distant organs through a range of mediators 3 .…”
Conceptıon and design of the study; acquisition, analysis and interpretation of data; technical procedures; statistics analysis; manuscript preparation and writing; final approval.
“…Histopathological changes in the jejunum due to IR injury were evaluated according to the grading of Chiu et al 3…”
Section: Measurementsmentioning
confidence: 99%
“…The pathogenesis of ischemia reperfusion (IR) is due to both the depletion of cellular energy sources due to tissue hypoxia during ischemia and, more importantly, to the formation of O2-derived free radicals during reperfusion. The IR process can cause dysfunction and damage not only to the organ in which it is involved but also to distant organs through a range of mediators 3 .…”
Conceptıon and design of the study; acquisition, analysis and interpretation of data; technical procedures; statistics analysis; manuscript preparation and writing; final approval.
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