The effects of subchorionic hematoma on pregnancy outcome in patients with threatened abortion

Abstract

Objective:To assess the effects of ultrasonographically detected subchorionic hematomas on pregnancy outcomes in patients with vaginal bleeding within the first half of pregnancy. Material and Methods:Patients diagnosed with threatened abortion due to painless vaginal bleeding and who were followed up in an inpatient service during the first vaginal bleeding between January 2009 and December 2010 were included in this retrospective cohort study. Patients were divided into two groups according to the presence of subchorionic hematoma. Miscarriage rates and pregnancy outcomes of ongoing pregnancies were compared between the groups.Results: There were no statistically significant differences between the groups regarding demographic parameters, including age, parity, previous miscarriage history, and gestational age at first vaginal bleeding. While 13 of 44 pregnancies (29.5%) with subchorionic hematoma resulted in miscarriage, 25 of 198 pregnancies (12.6%) without subchorionic hematoma resulted in miscarriage (p=.010). The gestational age at miscarriage and the duration between first vaginal bleeding and miscarriage were similar between the groups. The outcome measures of ongoing pregnancies, such as gestational week at delivery, birth weight, and delivery route, were also similar between the groups. Conclusion:Ultrasonographically detected subchorionic hematoma increases the risk of miscarriage in patients with vaginal bleeding and threatened abortion during the first 20 weeks of gestation. However, it does not affect the pregnancy outcome measures of ongoing pregnancies. (J Turk Ger Gynecol Assoc 2014; 15: 239-42) Key words: Abortion, threatened, miscarriage, spontaneous, pregnancy outcome Received: 02 September, 2014 Accepted: 09 October, 2014 The effects of subchorionic hematoma on pregnancy outcome in patients with threatened abortion

Doppler and biochemical assessment for the prediction of early pregnancy outcome in patients experiencing threatened spontaneous abortion

“…Intrauterine blood pooling was identified in three women in the spontaneous abortion group by ultrasonography. The difference between the groups was significant, in agreement with the findings of Sukur et al, 21 who reported an increased risk of spontaneous abortion in women with an ultrasonographically detected subchorionic hematoma in the first 20 weeks of pregnancy. However, it does not influence late pregnancy outcomes.…”

“…The difference between the groups was significant, in agreement with the findings of Sukur et al,21 who reported an increased risk of spontaneous abortion in women with an ultrasonographically detected subchorionic hematoma in the first 20 weeks of pregnancy. The difference between the groups was significant, in agreement with the findings of Sukur et al,21 who reported an increased risk of spontaneous abortion in women with an ultrasonographically detected subchorionic hematoma in the first 20 weeks of pregnancy.…”

Insights on the Use of α-Lipoic Acid for Therapeutic Purposes

“…Sub-chorionic hematoma is a sonographically detected anechoic area with a falciform shape that increases the risk of spontaneous abortion [131]. Placental dysfunction, insufficient angiogenesis, and chronic inflammation are underlying causes of early pregnancy bleeding, and these factors can even result in preterm labor or perinatal mortality [132]. Progesterone has a significant role both in maturation of fetus and cytokine balance.…”

Application of a Nomogram for Predicting the Risk of Subchorionic Hematoma in Early Pregnancy With In Vitro Fertilization-Embryo Transfer/Frozen Embryo Transfer

“…A study reported that the presence of SCH in patients who underwent IVF-ET/FET had no influence on the incidence of spontaneous miscarriage or live birth rate (15). As for natural pregnancies, however, most studies have suggested a significant correlation between SCH and adverse obstetric outcomes (2,33). Moreover, the occurrence of SCH could increase the risk of spontaneous miscarriage, premature delivery, placental abruption, and gestational hypertension (34)(35)(36)(37).…”

“…If the hematoma is large and clots have formed, petechial or linear hyperechoic areas can be detected around the gestational sac and under the chorionic membrane, whose lower edges are mostly connected to the inner cervical canal. The existence of SCH is possibly related to the occurrence of adverse obstetric outcomes, such as miscarriage (2). However, the induction of SCH remains unclear, and the occurrence of SCH is reportedly related to thrombosis (3).…”