The Effects of Stress on Cognitive Aging, Physiology and Emotion (ESCAPE) Project

Scott, Stacey B.; Graham‐Engeland, Jennifer E.; Engeland, Christopher G.; Smyth, Joshua M.; Almeida, David M.; Katz, Mindy J.; Lipton, Richard B.; Mogle, Jacqueline; Muñoz, Elizabeth; Ram, Nilam; Sliwinski, Martin J.

doi:10.1186/s12888-015-0497-7

Cited by 141 publications

(111 citation statements)

References 78 publications

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“…See Table 1 for a general overview of sample characteristics and study designs. The Effects of Stress on Cognitive Aging, Physiology, and Emotions (ESCAPE) study examined whether repetitive thinking helps explain how stressors affect cognitive health over time (for details see Scott et al, 2015). The Stress and Working Memory (SAWM) study examined relationships between stress and personality, health status, and working memory (for details see Mogle et al, 2019).…”

Section: Methodsmentioning

confidence: 99%

Understanding stress reports in daily life: a coordinated analysis of factors associated with the frequency of reporting stress

et al. 2019

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Although stress is a common experience in everyday life, a clear understanding of how often an individual experiences and reports stress is lacking. Notably, there is little information regarding factors that may influence how frequently stress is reported, including which stress dimension is measured (i.e., stressors—did an event happen, subjective stress—how stressed do you feel, conditional stress—how stressful a stressor was) and the temporal features of that assessment (i.e., time of day, day of study, weekday vs. weekend day). The purpose of the present study was to conduct a coordinated analysis of five independent ecological momentary assessment studies utilizing varied stress reporting dimensions and temporal features. Results indicated that, within days, stress was reported at different frequencies depending on the stress dimension. Stressors were reported on 15–32% of momentary reports made within a day; across days, the frequency ranged from 42 to 76% of days. Depending on the cutoff, subjective stress was reported more frequently ranging about 8–56% of all moments within days, and 40–90% of days. Likewise, conditional stress ranged from just 3% of moments to 22%, and 11–69% of days. For the temporal features, stress was reported more frequently on weekdays (compared to weekend days) and on days earlier in the study (relative to days later in the study); time of day was inconsistently related to stress reports. In sum, stress report frequency depends in part on how stress is assessed. As such, researchers may wish to measure stress in multiple ways and, in the case of subjective and conditional stress with multiple operational definitions, to thoroughly characterize the frequency of stress reporting.

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Section: Methodsmentioning

confidence: 99%

Understanding stress reports in daily life: a coordinated analysis of factors associated with the frequency of reporting stress

et al. 2019

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“…Importantly, a significant reduction in lipid peroxidation by L has been demonstrated in vivo for newborn infants, who are at substantial risk of oxidative stress, given the intense metabolic nature of development and low stores of diet-based antioxidants [46,47]. Moreover, L has been found to have meaningful anti-inflammatory action [48,49], which could serve to modulate the many negative effects of inflammation associated not only with injury and disease, but also that brought on by psychological stress [50]. …”

Section: Lutein and Nitric Oxide: A Homeostatic Symbiosismentioning

confidence: 99%

Nitric Oxide and Lutein: Function, Performance, and Protection of Neural Tissue

Stringham

2015

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The soluble gas neurotransmitter nitric oxide (NO) serves many important metabolic and neuroregulatory functions in the retina and brain. Although it is necessary for normal neural function, NO can play a significant role in neurotoxicity. This is often seen in disease states that involve oxidative stress and inflammation of neural tissues, such as age-related macular degeneration and Alzheimer’s disease. The dietary xanthophyll carotenoid lutein (L) is a potent antioxidant and anti-inflammatory agent that, if consumed in sufficient amounts, is deposited in neural tissues that require substantial metabolic demand. Some of these specific tissues, such as the central retina and frontal lobes of the brain, are impacted by age-related diseases such as those noted above. The conspicuous correspondence between metabolic demand, NO, and L is suggestive of a homeostatic relationship that serves to facilitate normal function, enhance performance, and protect vulnerable neural tissues. The purpose of this paper is to review the literature on these points.

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“…The negative association may be partially due to the smaller hippocampal subfield volumes caused by prolonged exposure to stress, and it remained unchanged after individuals with clinically significant symptoms of depression were removed . Moreover, researchers proposed that unconstructive repetitive thought was the mediator between stress and cognitive function . In the long term, it caused dysregulation of hypothalamic‐pituitary‐adrenal axis function and inflammation, which accelerated cognitive decline .…”

Section: Discussionmentioning

confidence: 99%

“…48 Moreover, researchers proposed that unconstructive repetitive thought was the mediator between stress and cognitive function. 49 In the long term, it caused dysregulation of hypothalamic-pituitary-adrenal axis function and inflammation, which accelerated cognitive decline. 49 The results support the need to include psychosocial assessment in cognitive impairment screenings for older adults.…”

Section: Discussionmentioning

confidence: 99%

Information processing speed as a mediator between psychosocial stress and global cognition in older adults

et al. 2018

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Background: The link between psychosocial stress and cognitive function is complex, and previous studies have indicated that it may be mediated by processing speed. Therefore, the main aim of this study was to examine whether processing speed mediates the association between psychosocial stress and global cognition in older adults. Moreover, the moderating role of gender in this model is examined as well. Methods: The study included 2322 community-dwelling older adults in Malaysia who were randomly selected through a multistage proportional cluster random sampling technique. Global cognition construct was measured by the Mini-Mental State Examination and Montreal Cognitive Assessment; psychosocial stress construct was measured by perceived stress, depression, loneliness, and neuroticism; and processing speed was assessed by the Digit Symbol Substitution Test. Structural equation modelling was used to analyze the mediation and moderation tests. Results: Processing speed was found to partially mediate the relationship between psychosocial stress and global cognition (β in the direct model = −0.15, P < 0.001; β in the full mediation model = −0.11, P < 0.001). Moreover, the relationship between psychosocial stress and global cognition was found to be significant in men only, whereas the association between processing speed and global cognition was significant in men and women. Conclusions: Psychosocial stress may increase the likelihood that older adults will experience poor processing capacity, which could reduce their higher level cognition. Results indicate that there is a need to develop processing capacity intervention programmes for psychologically distressed older adults to prevent them from suffering cognitive decline.

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The Effects of Stress on Cognitive Aging, Physiology and Emotion (ESCAPE) Project

Cited by 141 publications

References 78 publications

Understanding stress reports in daily life: a coordinated analysis of factors associated with the frequency of reporting stress

Understanding stress reports in daily life: a coordinated analysis of factors associated with the frequency of reporting stress

Nitric Oxide and Lutein: Function, Performance, and Protection of Neural Tissue

Information processing speed as a mediator between psychosocial stress and global cognition in older adults

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