“…Nobel laureate Leontief (1951a) originally introduced IOTs as a statistical tool to analyze his country's economy. They are widely used by national statistical offices ( Eurostat, 2008 ) to compute the impact of an economic sector on a national economy ( George, 2019 ), its employment rate ( Fuster et al, 2019 ; Gala et al, 2018 ; Garrett-Peltier, 2017 ), or, for instance, to assess the effect of the introduction of a new policy ( Liu et al, 2009 ; Zanchetta Borghi, 2017 ). Recently, the IOTs have been applied on a multi-regional scale ( Zhou et al, 2018 ; Faturay et al, 2020 ; Bolea et al, 2021 ; Fan and Liu, 2021 ) using the multi-regional IOT (MRIO) on the evaluation of environmental impact through the environmental extended (EIO) ( De Haan and Keuning, 1996 ) or physical (PIOTs) ( Hubacek and Sun, 2001 ; Dietzenbacher et al, 2009 ; Wachs and Singh, 2018 ) IOTs and on the expansion of the boundary conditions of life cycle assessment (LCA) studies through the IO-based hybrid-LCA ( Wang et al, 2020 ).…”