The effects of resveratrol intake on weight loss: a systematic review and meta-analysis of randomized controlled trials

The effects of grape seed extract (Vitis vinifera) supplement on inflammatory markers, neuropeptide Y, anthropometric measures, and appetite in obese or overweight individuals: A randomized clinical trial

“…Anti‐obesity effects of GSE or bioactive constitutes of grapes has attracted much attention. In agreement with the present study, some investigations showed that dietary intake of phenolic compounds such as flavonoid, resveratrol, and anthocyanins may have a beneficial role in weight management (Azzini, Giacometti, & Russo, ; Bertoia et al, ; Jennings, MacGregor, Spector, & Cassidy, ; Tabrizi et al, ). The main proposed mechanisms for effects of phenolic compounds of GSE on obesity management are anti‐hypertrophic and anti‐adipogenic activities in visceral white adipose tissue (Pascual‐Serrano et al, ), lipolysis stimulation, increase in hepatic fat oxidation through postprandial lipolysis augmentation (Vogels et al, ), delay in absorption, decrease in food digestibility (Tebib, Besançon, & Rouanet, ; Vogels et al, ) and reduction in appetite or food intake (Preuss et al, ; Tebib et al, ).…”

The effects of resveratrol on lipid profiles and liver enzymes in patients with metabolic syndrome and related disorders: a systematic review and meta-analysis of randomized controlled trials

“…We found that resveratrol supplementation among patients with MetS and related disorders significantly reduced total cholesterol, but did not affect triglycerides, LDL-, HDL-cholesterol concentrations. Previously, the effects of resveratrol on weight loss [49] and biomarkers of inflammation and oxidative stress among patients with Table 2 The association between resveratrol intake on lipid profiles and liver enzymes using subgroup analysis (Continued) MetS [50], and coenzyme Q10 on lipid profiles among patients diagnosed with coronary artery disease [51] were assessed. In a study conducted by Simental-Mendia et al [46], resveratrol supplementation at a dosage of 100 mg/day for 8 weeks to individuals with dyslipidemia significantly decreased total cholesterol and triglycerides concentrations.…”

Resveratrol and Its Effects on the Vascular System

“…Similar conclusions were drawn in a meta-analysis that encompassed 36 randomized clinical trials accomplished until July 2018. Here, resveratrol intake significantly decreased body weight, BMI, fat mass, and waist circumference [132], demonstrating altogether the positive effects of resveratrol supplementation on weight loss. Although data of how resveratrol affects blood pressure are rather heterogeneous and partly controversial, positive blood pressure-lowering effects were concluded in a recent analysis of 17 randomized controlled clinical trials, in either individuals receiving more than 300 mg per day of resveratrol, or in diabetic patients [133].…”