The effects of renal transplantation on diabetic retinopathy: Clinical course and visual outcomes

Roy, Rupak; Das, Manmath Kumar; Pal, Bikramjit P; Ganesan, Suguneswari; Raman, Rajiv; Sharma, Tarun

doi:10.4103/0301-4738.121067

Cited by 17 publications

(9 citation statements)

References 17 publications

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“…In a study done to assess the course of DR after renal transplant, it was found that renal transplant stabilized retinopathy in the majority (60%) of the diabetic patients and significant improvement in visual acuity was seen during the first 20 months postrenal transplant. [ 42 ]…”

Section: Renal Status and Diabetic Retinopathymentioning

confidence: 99%

Does tight control of systemic factors help in the management ofdiabetic retinopathy?

Rajalakshmi¹,

Prathiba²,

Mohan³

2016

Indian J Ophthalmol

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Diabetic retinopathy (DR), one of the leading causes of preventable blindness, is associated with many systemic factors that contribute to the development and progression of this microvascular complication of diabetes. While the duration of diabetes is the major risk factor for the development of DR, the main modifiable systemic risk factors for development and progression of DR are hyperglycemia, hypertension, and dyslipidemia. This review article looks at the evidence that control of these systemic factors has significant benefits in delaying the onset and progression of DR.

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Section: Renal Status and Diabetic Retinopathymentioning

confidence: 99%

Does tight control of systemic factors help in the management ofdiabetic retinopathy?

Rajalakshmi¹,

Prathiba²,

Mohan³

2016

Indian J Ophthalmol

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“…Most importantly, however, KTx by itself can stabilise retinopathy. [ 4 , 5 ] Another frequent comorbidity is hypertension (HT), that may damage retinal vessels. That is why fundoscopy is important, particularly with evaluation of retinal vessels.…”

Section: Introductionmentioning

confidence: 99%

A 10-year monitoring of the eyesight in patients after kidney transplantation

Raczyńska

Ślizień²,

Bzoma

et al. 2018

Medicine

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A pilot study of a 10-year analysis of the eyesight characteristics in patients after renal transplantation with a view to a later wider study of the same population.The study encompassed 50 eyes in 25 patients who underwent renal transplantation in the years 2007 and 2008. All patients underwent: visual acuity measurement, tonometry, slit lamp examination, and spectroscopic optical coherence tomography.Changes in the eyes observed during the 10-year observation period included mostly: cataract (48%), hypertensive angiopathy (28%), diabetic macular edema (16%), and glaucoma (16%). Ten years after the renal transplant visual acuity declined in 15 patients (60%). In 67% of those with eyesight deterioration the cause was cataract, while in patients with no changes in the eyesight (n = 10) cataract was diagnosed only in one. Patients with cataracts had been more often treated with cyclosporine, and that difference was statistically significant (73% vs 21%; P < .05). Comparing patients with hypertensive angiopathy with controls has shown that in the first group creatinine levels were statistically significantly higher (1.6 vs 1.16 mg/dL; P < .05). Patients with angiopathy had been also longer on renal replacement therapy before transplant (57 vs 26 months, P > .05), and this group included also statistically more persons after retransplantation (43% vs 5%, P < .05).Most frequent ophthalmological diagnoses in patients after a kidney transplant include cataract, diabetic retinopathy, and hypertensive angiopathy. Visual acuity deterioration was seen in 60% of patients and was mainly the effect of cataract progress. The effect of cyclosporine on cataract progress was significant. The diagnosis of hypertensive angiopathy corresponded with poorer function of the transplanted kidney.

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“…We read with interest the article titled “The effects of renal transplantation on diabetic retinopathy: Clinical course and visual outcomes.”[ 1 ]…”

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confidence: 99%