The Effects of Qingfei Paidu Decoction on Coronavirus Disease-19: A Narrative Review

Abstract

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Efficacy and safety of integrated traditional Chinese and Western medicine against COVID‐19: A systematic review and meta‐analysis

“…There was an in vitro study finding that Qingfei Paidu Decoction could dose‐dependently inhibit the replication of coronavirus at the levels of RNA and protein. Furthermore, it has shown that Qingfei Paidu Decoction can not only inhibit the absorption of viruses into cells but also act as an antiviral agent by upregulating the expression of interferon and interferon‐stimulated genes (Wang, Y, Wu, et al, 2021 ). Other studies have also proved that Lianhua Qingwen Granule can reduce the impact of the virus to host cells by blocking multiple binding sites of angiotensin‐converting enzyme to SARS‐COV‐2 in the human body (Niu M, Wang, et al, 2020).…”

Effect of Qingfei Paidu decoction combined with Western medicine treatments for COVID-19: A systematic review and meta-analysis

“…QFPDD consists of four classic Chinese medicine prescriptions, i.e., Shegan Mahuang decoction, Maxing Shigan decoction, Xiaochaihu decoction, and Wuling powder, and contains 21 main herbal components ( Table 1 ). Previous studies reported that QFPDD has good effectiveness on COVID-19 and can effectively prevent the worse disease progress, improve clinical symptoms and absorption of lung lesions, reduce death rates, while no serious adverse reactions have been reported ( Chen et al,2020b ; Ji et al, 2021 ; Kang et al,2020 ; Luo et al,2021 ; Ma et al, 2020 ; Ren et al, 2020 ; Shi et al, 2020 ; Wang et al,2021b ; Zhang et al,2021 ) . Notably, a study from South Korea showed that QFPDD was the most prescribed herbal medicine for COVID-19 in Korea in the first days of the disease and was the second most prescribed medicine across the whole course.…”

Analysis of Herbal Medicine in the Clinical Guidelines of Korea and China for COVID-19

“…淸肺排毒湯은 코로나-19의 증상인 발열, 기침 등 의 폐렴 증상의 개선, 혈액 검사상 림프구 백분율, AST(Aspartate Aminotransferase), ALT(Alanine Aminotransferase), D-dimer 등의 정상화, 폐 CT 영상 소견 개선에 도움이 된다고 보고된 바 있다 16…”