The Effects of Protein Malnutrition on Wound Contraction: An Experimental Study

Effects of Protein Deprivation on α1(I) and α1(III) Collagen and Its Degrading System in Rat Skin

“…Inappropriate protein nutrition can thus cause, for example, retardation of wound-healing and deterioration of bedsores. 1,2) Deterioration of the skin such as that occurring with epilation and achromia is one of the serious symptoms of kwashiorkor.…”

Healing Impairment of Open Wounds by Skin Irradiation

“…Since most uncomplicated wounds in normal skin of healthy people heal without significant problems, models of impaired healing were developed to mimic clinical conditions that impair healing in patients. Wound healing models involving the administration of chemotherapy, 2–7 radiotherapy, 8–13 infection of wounds, 14 malnutrition of animals, 15 the creation of a diabetic state, 16–18 and ischemia 19 have been created to study impairment of normal wound healing. Radiation‐impaired wound healing models have the advantage of being able to treat skin locally, without exerting a systemic effect on the treated animal.…”

Effect of Protein Malnutrition on the Skin Epidermis of Hairless Mice

“…PM affects the metabolism of several body proteins, resulting in the malfunction in a number of body parts, including the skin. Inappropriate protein nutrition can thus cause, for example, retardation of wound healing and deterioration of bedsores [23,24]. Deterioration of the skin such as that occurring with epilation and achromia is one of the serious symptoms of kwashiorkor [29,33].…”