The effects of protein deprivation upon the oral tissues of the rat and particularly upon periodontal structures under irritation

Acquired immune suppression and other risk factors/indicators for periodontal disease progression

“…Severe protein deficiency (kwashiorkor) is associated with an increased incidence and severity of acute necrotizing gingivitis, periodontitis and cancrum oris (noma) (70,182). Protein deficiency in animal models has demonstrated osteoporosis in alveolar bone, degeneration of the periodontal ligament, decreased cementum deposition and delayed wound healing; however, periodontal pocketing does not occur in the absence of plaque (37,42,80,(217)(218)(219). An alteration in resistance to periodontal disease due to mild protein deficiency has not been supported in the literature (43,44).…”

Effects of Stress on the Periodontal Tissues of Young Adult Male Rats and Hamsters

“…A VARIETY of stressing agents have been used in an attempt to study their effects on the periodontal tissues of experimental animals. [1][2][3][4][5][6][7][8] Fedi 7 produced stress in young hamsters by successive exposure to cold, water bath and violent exercise, and a subcutaneous injection of 10 percent formaldehyde. He noted minor changes in the periodontal membrane fibers and fibroblasts.…”

Nutrition, Diet, and Calcium Metabolism in Dental Health

“…In protein deficiency degeneration of the connective tissue of the gingiva and periodontal membrane has been observed, associated with osteoporosis of the alveolar bone and retardation of cementum formation.7 The effect of local irritants is accentuated under these conditions. 8 No information is available on the relationship between dietary fats and periodontal disease. In faulty carbohydrate metabolism as encountered in diabetes mellitus, the inflammatory response in gingivitis has been reported as more severe than in nondiabetic patients.…”