The effects of propranolol on skeletal muscle contraction, lipid peroxidation products and antioxidant activity in experimental hyperthyroidism

Zakaria, Zaiton; Merican, Z.; Khalid, B. A. K.; Mohamed, Jamaludin; Baharom, Shahrizan

doi:10.1016/0306-3623(93)90034-u

Cited by 31 publications

(26 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Thus, no significant change (TBARS) or decrease (HPs) were observed in lipid peroxidation level in the testis from adult hyperthyroid rats [122], and the thyroid hormone-induced increase in lipid peroxidation was found to be confined to some skeletal muscles. In both rat [11,12] and cat [123], such an increase was found in the soleus, a red muscle mainly composed of slow-twitch oxidative glycolitic fibres (type I). Conversely, no change was found in the extensor digitorum longus (EDL) [11,123], a white muscle mainly composed of fast-twitch glycolitic fibres (Type IIb).…”

Section: Oxidative Stress In Experimental Hyperthyroidism and Hypothymentioning

confidence: 93%

“…In both rat [11,12] and cat [123], such an increase was found in the soleus, a red muscle mainly composed of slow-twitch oxidative glycolitic fibres (type I). Conversely, no change was found in the extensor digitorum longus (EDL) [11,123], a white muscle mainly composed of fast-twitch glycolitic fibres (Type IIb). These results are consistent with early observations that red, but not white muscles, are sensitive to thyroid hormones [124,125].…”

Section: Oxidative Stress In Experimental Hyperthyroidism and Hypothymentioning

confidence: 93%

“…Zaiton et al [123] revealed increased concentration of lipid peroxidation products in the myocardium and solear muscle in rat, but not in liver tissue. Conflicting results obtained Fernandez et al [10] : increased liver content in lipid peroxides induced by thyroid hormones.…”

Section: Oxidative Stress In Experimental Hyperthyroidism and Hypothymentioning

confidence: 96%

See 2 more Smart Citations

Oxidative Stress and Antioxidant Status in Hypo- and Hyperthyroidism

Petrulea¹,

Muresan²,

Duncea³

2012

Antioxidant Enzyme

View full text Add to dashboard Cite

Section: Oxidative Stress In Experimental Hyperthyroidism and Hypothymentioning

confidence: 93%

Section: Oxidative Stress In Experimental Hyperthyroidism and Hypothymentioning

confidence: 93%

See 1 more Smart Citation

Oxidative Stress and Antioxidant Status in Hypo- and Hyperthyroidism

Petrulea¹,

Muresan²,

Duncea³

2012

Antioxidant Enzyme

View full text Add to dashboard Cite

“…A T 3 regulate basal metabolic rate and are essential for the maintenance and constant body temperature and protein and lipid metabolism (Collin et al, 2005;Lu et al, 2007). Also during development, T 3 stimulate both growth and differentiation of organs, their action can be direct, indirect or permissive (Zation et al, 1993). Also, T 3 acts together with insulin to elevate the rate of lipogenesis in chicken hepatocytes in vitro (Wilson et al, 1986).…”

mentioning

confidence: 99%

Effect of Artificial and Natural Day Light Intensities on some Behavioral Activities, Plumage Conditions, Productive and Physiological Changes for Japanese Quail

Khalil¹,

Hanafy²,

Hamdy³

2015

Asian J. of Poultry Science

View full text Add to dashboard Cite

This study was designed to evaluate the effects of different artificial light intensity; 10, 50, 250, 500 lux and natural day light (NDL, average 375 lux) from 3-18 week of age on behavioral activities, plumage conditions, productive and physiological traits for grower and layer of Japanese quail. A total of 270 Japanese quails chicks (3 week old) were randomly assigned to five treatment groups according to different light intensities. The results showed that the birds subjected at NDL and 250 lux spent significantly more time standing than those recorded in 50 and 500 lux groups. Also, birds kept at 500 lux spent significantly more time walking compared with other groups. The lowest plumage deterioration was detected in birds kept under NDL compared with other experimental groups. The heavier body weight (p#0.05) at 6 weeks and weight gain from 3-6 weeks were detected for birds reared at NDL and 250 lux compared with 500 lux and did not significant with the rest of the experimental groups. While, Hen Day Egg Production (HDEP) and Total Egg Mass (TEM) were linearly increased beginning of 50 lux with increasing light intensity. Fertility percentage was significantly higher in 250 lux group than in 50 lux and was not significant with the other groups. Hatchability percentage was significantly decreased in 10 lux group compared with the other groups. Serum level of T 3 was decreased linearly with increasing light intensity. Birds kept at 500 lux had reduced overall number of Ovarian Yellow Follicle (OYF), relative weight of ovaries and testes and cloacal gland area compared with the other groups. From our results, it could be concluded that neither high light intensity (500 lux) nor low light intensity (10 lux) had a positive effect on most traits. Therefore, to maximize productive, reproductive parameters and increase revenue economic may be by using moderate artificial light intensity if we used closed-side housing system or NDL if we used open side housing system for production of Japanese quail.

show abstract

“…The limited existing literature is controversial. A hyperthyroid state has been reported to consistently decrease the isometric twitch tension and contraction time [Merican and Morat, 1984;Merican et al, 1992;Zaiton et al, 1993], but to either decrease [Zaiton et al, 1993] or maintain the maximum tetanic tension (Po) at control levels [Merican and Morat, 1984]. To our knowledge, the effects of elevated thyroid hormone levels on Vmax and of depressed thyroid hormone levels on any mechanical property of the cat soleus muscle have not been determined.…”

Section: Introductionmentioning

confidence: 93%

Effect of Altered Thyroid State on the in situ Mechanical Properties of Adult Cat Soleus

Roy

Zhong²,

Hodgson³

et al. 2003

Cells Tissues Organs

View full text Add to dashboard Cite

To determine the responsiveness of cat hindlimb muscles to thyroid manipulation, adult female cats were made hypothyroid (thyroidectomy plus tapazole treatment), hyperthyroid (synthroid pellets), or maintained euthyroid. After 4 months, the hypothyroid soleus had slower time-to-peak (TPT, 80%) and half-relaxation (HRT) times, whereas the hyperthyroid soleus had faster TPT (20%) and HRT than euthyroid cats. The tension at low stimulation frequencies (5–15 Hz) was higher in hypothyroid and lower in hyperthyroid cats compared to euthyroid cats. Muscle weight, maximum twitch and tetanic (Po) tensions, and maximum rates of shortening (Vmax) were similar across groups. The soleus of hypothyroid cats was more fatigable than normal. The myosin heavy chain (MHC) composition, based on gel electrophoresis, was unaffected by thyroid hormone manipulation. Based on the reaction of monoclonal antibodies for specific MHCs, some fast fibers in the hypothyroid cats coexpressed developmental MHC. These data indicate that 4 months of an altered thyroid state result in changes in the isometric twitch speed properties of the cat soleus, but not the tension-related or isotonic properties. Further, a chronic decrease in thyroid hormone had a greater impact than a chronic increase in thyroid hormone on the mechanical properties of the adult cat soleus.

show abstract

The effects of propranolol on skeletal muscle contraction, lipid peroxidation products and antioxidant activity in experimental hyperthyroidism

Cited by 31 publications

References 13 publications

Oxidative Stress and Antioxidant Status in Hypo- and Hyperthyroidism

Oxidative Stress and Antioxidant Status in Hypo- and Hyperthyroidism

Effect of Artificial and Natural Day Light Intensities on some Behavioral Activities, Plumage Conditions, Productive and Physiological Changes for Japanese Quail

Effect of Altered Thyroid State on the in situ Mechanical Properties of Adult Cat Soleus

Contact Info

Product

Resources

About