1998
DOI: 10.1213/00000539-199811000-00035
|View full text |Cite
|
Sign up to set email alerts
|

The Effects of Propofol, Isoflurane, and Sevoflurane on Oxygenation and Shunt Fraction During One-Lung Ventilation

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

3
40
1
2

Year Published

1999
1999
2013
2013

Publication Types

Select...
6
2

Relationship

0
8

Authors

Journals

citations
Cited by 105 publications
(46 citation statements)
references
References 20 publications
3
40
1
2
Order By: Relevance
“…Dogs have intense hypoxemic pulmonary vasoconstriction 63,64 that should protect them against blood flow redistribution during PEEP and 1‐lung ventilation. However, anesthesia with isoflurane and sevoflurane has been shown to abolish this phenomenon in a dose‐dependent fashion 8,64,65 . Because in our experiment dogs were anesthetized with isoflurane, blood flow redistribution to the nonventilated lung could have occurred.…”
Section: Discussionmentioning
confidence: 84%
“…Dogs have intense hypoxemic pulmonary vasoconstriction 63,64 that should protect them against blood flow redistribution during PEEP and 1‐lung ventilation. However, anesthesia with isoflurane and sevoflurane has been shown to abolish this phenomenon in a dose‐dependent fashion 8,64,65 . Because in our experiment dogs were anesthetized with isoflurane, blood flow redistribution to the nonventilated lung could have occurred.…”
Section: Discussionmentioning
confidence: 84%
“…Im Vergleich zum bisherigen Standard -Isofluran -scheint sich Sevofluran kaum anders zu verhalten, während Propofol eher eine Verminderung der Shuntfraktion und damit eine bessere Oxygenierung bewirkt [14,15,16]. Im Vergleich zum bisherigen Standard -Isofluran -scheint sich Sevofluran kaum anders zu verhalten, während Propofol eher eine Verminderung der Shuntfraktion und damit eine bessere Oxygenierung bewirkt [14,15,16].…”
Section: ᭤ Hochfrequenz-jetbeatmungunclassified
“…One important pathophysiologic mechanism during OLV is hypoxic pulmonary vasoconstriction (HPV). During OLV, HPV may reduce venous admixture and limit the fall in P a O 2 by diverting pulmonary blood flow from the nonventilated to the ventilated lung 16 . Intravenous anesthetic agents do not seem to affect HPV, whereas inhalation agents inhibit HPV in a dose‐dependent manner.…”
Section: Discussionmentioning
confidence: 99%
“…Intravenous anesthetic agents do not seem to affect HPV, whereas inhalation agents inhibit HPV in a dose‐dependent manner. When inhalation anesthesia is used for OLV an increase in intrapulmonary shunt fraction and a reduction in arterial oxygen tension have been reported in humans 16,17 . In healthy dogs, a significant decrease in P a O 2 and increase in P(A‐a)O 2 gradient was reported during OLV 1,3 .…”
Section: Discussionmentioning
confidence: 99%