The effects of prolonged physical exercise on renal function, electrolyte balance and muscle cell breakdown

Gerth, Jens; Ott, U.; Fünfstück, R; Bartsch, Rupert; Keil, E; Schubert, Kurt; Hübscher, Johanna; Scheucht, S; Stein, G

doi:10.5414/cnp57425

Cited by 44 publications

(41 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, no differences between BCAA and CON could be found. Creatinine clearance, glomerular filtration rate, fractional sodium excretion and fractional urea excretion decreased, reflecting reduced renal function (1,8) in both BCAA and CON. The concentrations of urea in plasma and urine were not different between BCAA and CON.…”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

“…In recent years, studies investigated athletes participating in ultra-marathons over 100 km ( 1 ) or even longer ( 2 , 3 ). Marathon and especially ultra-marathon running as an eccentric exercise may cause skeletal muscle damage resulting in an increase in myocellular enzymes such as plasma creatine kinase (1)(2)(3) and myoglobin ( 1 ). Skeletal muscle damage and the corresponding increase in myocellular enzymes in plasma may lead to rhabdomyolysis, thus causing an impairment of renal function ( 4 ), reflected by a decline in the post-race creatinine clearance ( 5 ) and even renal failure in ultra-marathoners ( 6 ).…”

mentioning

confidence: 99%

See 2 more Smart Citations

Branched-Chain Amino Acid Supplementation during a 100-km Ultra-Marathon^|^mdash;A Randomized Controlled Trial

Knechtle

Mrazek²,

Wirth³

et al. 2012

J Nutr Sci Vitaminol

View full text Add to dashboard Cite

Summary Ultra-marathon running is supposed to increase the parameters of skeletal muscle damage and impair renal function. The purpose of this study was to investigate the effect of branched-chain amino acid supplementation on skeletal muscle damage and renal function during a 100-km ultra-marathon. Twenty-eight athletes were randomly divided into two groups, one group using branched-chain amino acid supplementation (BCAA) and a control group (CON). The athletes in the BCAA group were supplemented with a total of 50 g of an amino acid concentrate including 20 g of BCAA. The intake of energy, antioxidants and parameters of both skeletal muscle damage and renal function were determined. Race time was not different between BCAA and CON when controlled for the personal best time in a 100-km ultra-marathon. Neither the intake of energy and antioxidants nor the parameters of skeletal muscle damage and renal function were different between BCAA and CON. We concluded that BCAA-supplementation before and during a 100-km ultra-marathon had no effect on performance, skeletal muscle damage or renal function.

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Branched-Chain Amino Acid Supplementation during a 100-km Ultra-Marathon^|^mdash;A Randomized Controlled Trial

Knechtle

Mrazek²,

Wirth³

et al. 2012

J Nutr Sci Vitaminol

View full text Add to dashboard Cite

show abstract

“…doubly labelled water) has not been measured to test the association between it and 24 h urinary K. The measurement of 24 h urinary K excretion has the advantage over other biochemical methods of being non-invasive and inexpensive. It should be noted, however, that K excretion via the urine varies depending on age, sex, the amount of physical activity undertaken and BMI (10,(43)(44)(45) , for which adjustment was made in the present study. Furthermore, it must be stated that using the 24 h urine method has some limitations.…”

Section: Discussionmentioning

confidence: 99%

Relationship between 24 h urinary potassium and diet quality in the adult Spanish population

Rodríguez-Rodríguez

Ortega

Carvajales

et al. 2014

Public Health Nutr.

View full text Add to dashboard Cite

Objective: To study the relationship between diet quality and 24 h urinary K excretion. Design: K was measured in 24 h urine samples, while diet was studied using a 24 h recall method over two consecutive days. Diet quality was determined using the Healthy Eating Index (HEI). The body weight, height and body composition of all participants were recorded, and the BMI of each calculated. Setting: Representative members of the adult Spanish population from the FANPE Study ('Fuentes Alimentarias de Nutrientes en Población Española'; Dietary Sources of Nutrients in the Spanish Population). Subjects: The final sample size was 329 participants aged 18-60 years. Results: Participants with a 24 h urinary K excretion ≥ 93 mmol/d (group AP = adequate potassium) had greater self-reported K intakes, consumed more fruit and vegetables, had a more varied diet and had better HEI scores than those with a 24 h urinary K excretion < 93 mmol/d (group IP = inadequate potassium). A significant positive correlation was seen between 24 h urinary K and dietary variety and the number of servings of fruits, vegetables and dairy products consumed, and between each of these and the HEI after correcting for age, sex, BMI, coefficient of activity, energy intake and the under-reporting of energy intake. AP participants were less likely to have an inadequate diet (HEI score < 50) than IP participants (OR = 0·439; 95 % CI 0·201, 0·961; P = 0·039). Conclusions: Diet quality, measured by the HEI, is correlated with 24 h urinary K excretion in Spanish adults.

show abstract

“…However, few hours after the competitions, the proteins level in urine tends to return to the physiological level (Gerth et al, 2002;Miyai & Ogata, 1990;Edes, Shah, & Thornton, 1990).…”

Section: Long Distance Run Induced Hydration and Kidney Function Chanmentioning

confidence: 99%

Long distance run induced hydration and kidney function changes in marathoners

Gonçalves

Aquino

Puggina

2015

Motriz: rev. educ. fis.

View full text Add to dashboard Cite

Abstract--The aim of the study was to verify the hydration status and the kidney function in marathoners during the training season and after a marathon race. Nine male runners were investigated during 12 weeks of training. Urine was collected in four moments; in the beginning (C1) and during (C2) the training program, before (C3) and after (C4) the competition. Urine pH was measured using reagent tapes, urine density with a refractometer, protein excretion by Bradford assay and erythrocytes and leucocytes by microscopy. Changes were observed when C-4 was compared to the other collection times for all variables investigated. It is possible to conclude that physical exertion induced important changes in the hydration status and glomerular membrane selectivity to macromolecules, modifying the kidney function of the marathoners in C4. Keywords: marathon, dehydration, kidney function, urine analysisResumo--"Corrida de longa distância induz a mudanças no estado de hidratação e na função renal em maratonistas." O objetivo do estudo foi verificar o estado de hidratação e a função renal de maratonistas durante uma temporada preparatória e após a competição. Foram estudados nove maratonistas durante 12 semanas de treinamento. A urina foi coletada em quatro momentos: antes (C1) e durante (C2) o protocolo de treinamento, antes (C3) e após (C4) a competição. Foram mensurados o pH a partir de tiras de reagentes, a densidade por meio do refratômetro, a proteinúria pelo ensaio de Bradford, concentração de eritrócitos e de leucócitos por microscopia. Alterações foram encontradas quando comparado o C-4 com as coletas anteriores para todas as variáveis estudadas. Pode-se concluir que o exercício físico induziu a modificações importantes no estado de hidratação dos corredores e na função da membrana glomerular, modificando assim, a função renal dos maratonistas no momento pós prova. Palavras-chave: maratona, desidratação, função renal, análises urináriasResumen--"Funcionamiento para un cambios de larga distancia inducido en el estado de hidratación y función renal en maratonistas." El objetivo del estudio fue determinar el estado de hidratación y la función renal en los corredores de maratón durante una temporada de preparación y después de la competición. Se estudiaron nueve corredores durante 12 semanas de entrenamiento. La orina se recogió en cuatro momentos: antes y durante el protocolo de entrenamiento, antes y después de la competición. PH de tiras reactivas, de densidad a través del refractómetro, proteinuria por Bradford ensayo, concentración de eritrocitos y leucocitos fueron medidos por microscopía. No se encontraron cambios al comparar el C-4 con las colecciones anteriores para todas las variables. Se puede concluir que el ejercicio induce cambios significativos en el estado de hidratación de los corredores y la función de la membrana glomerular, modificando de este modo la función renal del tiempo de maratón después de la carrera.Palabras claves: maratón, deshidratación, la función renal, análisis urinario

show abstract

The effects of prolonged physical exercise on renal function, electrolyte balance and muscle cell breakdown

Cited by 44 publications

References 0 publications

Branched-Chain Amino Acid Supplementation during a 100-km Ultra-Marathon^|^mdash;A Randomized Controlled Trial

Branched-Chain Amino Acid Supplementation during a 100-km Ultra-Marathon^|^mdash;A Randomized Controlled Trial

Relationship between 24 h urinary potassium and diet quality in the adult Spanish population

Long distance run induced hydration and kidney function changes in marathoners

Contact Info

Product

Resources

About