Objective: To determine the incidence of and risk factors for extrathoracic upper airway obstruction after pediatric cardiac surgery.Study Design: A retrospective chart review was performed on 213 patients less than 18 years of age who recovered from cardiac surgery in our multidisciplinary intensive care unit in 2012.Clinically significant upper airway obstruction was defined before performing the chart review as post-extubation stridor with at least one of the following: greater than two corticosteroid doses, receiving helium-oxygen therapy, or re-intubation. Multivariate logistic regression analysis was performed to determine independent risk factors for this complication.Results: Thirty-five patients (16%) with extrathoracic upper airway obstruction were identified.On bivariate analysis, patients with upper airway obstruction had greater surgical complexity, higher vasoactive medication requirements, and longer postoperative durations of endotracheal intubation. They were also more difficult to calm while on mechanical ventilation, as indicated by higher narcotic infusion doses and greater likelihood to receive dexmedetomidine or vecuronium. On multivariable analysis, adjunctive use of dexmedetomedine or vecuronium (odds ratio: 4.4, 95% confidence intervals: 1.8-10.5) remained independently associated with upper airway obstruction.
Conclusion:Extrathoracic upper airway obstruction is relatively common following pediatric cardiac surgery, especially in children who are difficult to calm while endotracheally intubated.Postoperative upper airway obstruction could represent an important outcome measure in future studies of optimal sedation practices in this patient population.2