The effects of position on gastric residual volume of premature infants in NICU

Khatony, Alireza; Abdi, Alireza; Karimi, Batol; Aghaei, Abbas; Brojeni, Hamidreza Saeidi

doi:10.1186/s13052-018-0591-9

Cited by 15 publications

(53 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Fifteen (26%) studies were from the UK [ 29 , 30 , 31 , 55 , 58 , 59 , 60 , 69 , 70 , 74 , 78 , 82 , 83 , 87 , 90 , 91 , 93 , 100 ], 13 (23%) from the US [ 29 , 30 , 35 , 38 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 56 , 67 , 68 , 72 , 75 , 98 , 99 ], 17 (30%) from non-UK European countries [ 34 , 51 , 52 , 53 , 54 , 61 , 62 , 63 , 64 , 65 , 66 , 71 , 77 , 79 , 84 , 86 , 94 , 95 , …”

Section: Resultsmentioning

confidence: 99%

Real-World Outcomes of Ivacaftor Treatment in People with Cystic Fibrosis: A Systematic Review

Duckers

Lesher

Thorat

et al. 2021

JCM

View full text Add to dashboard Cite

Cystic fibrosis (CF) is a rare, progressive, multi-organ genetic disease. Ivacaftor, a small-molecule CF transmembrane conductance regulator modulator, was the first medication to treat the underlying cause of CF. Since its approval, real-world clinical experience on the use of ivacaftor has been documented in large registries and smaller studies. Here, we systematically review data from real-world observational studies of ivacaftor treatment in people with CF (pwCF). Searches of MEDLINE and Embase identified 368 publications reporting real-world studies that enrolled six or more pwCF treated with ivacaftor published between January 2012 and September 2019. Overall, 75 publications providing data from 57 unique studies met inclusion criteria and were reviewed. Studies reporting within-group change for pwCF treated with ivacaftor consistently showed improvements in lung function, nutritional parameters, and patient-reported respiratory and sino-nasal symptoms. Benefits were evident as early as 1 month following ivacaftor initiation and were sustained over long-term follow-up. Decreases in pulmonary exacerbations, Pseudomonas aeruginosa prevalence, and healthcare resource utilization also were reported for up to 66 months following ivacaftor initiation. In studies comparing ivacaftor treatment to modulator untreated comparator groups, clinical benefits similarly were reported as were decreases in mortality, organ-transplantation, and CF-related complications. The safety profile of ivacaftor observed in these real-world studies was consistent with the well-established safety profile based on clinical trial data. Our systematic review of real-world studies shows ivacaftor treatment in pwCF results in highly consistent and sustained clinical benefit in both pulmonary and non-pulmonary outcomes across various geographies, study designs, patient characteristics, and follow-up durations, confirming and expanding upon evidence from clinical trials.

show abstract

Section: Resultsmentioning

confidence: 99%

Real-World Outcomes of Ivacaftor Treatment in People with Cystic Fibrosis: A Systematic Review

Duckers

Lesher

Thorat

et al. 2021

JCM

View full text Add to dashboard Cite

show abstract

“…Essa postura ainda diminui o número e a gravidade da regurgitação e do volume residual gástrico uma hora após a refeição, diminui os níveis de cortisol salivar, da frequência respiratória e do escore de sono, sugerindo a correlação entre essa postura e a diminuição da frequência de comportamentos de estresse nesses RN's. Suas desvantagens estão relacionadas com o aumento dos distúrbios ortopédicos e atraso no desenvolvimento muscular (KHATONY et al, 2019;TOSO et al, 2015;YIN;YANG et al, 2015).…”

Section: Considerações Finaisunclassified

“…Estudos citam que em supino os RNPT tem mais estresse do que na posição prona, contudo esta posição se associa com maior incidência de morte súbita infantil, menor variabilidade da frequência cardíaca (VFC) e maior atividade simpática durante o sono. Portanto, os bebês colocados em decúbito ventral devem estar sob monitoração cardiopulmonar e de saturação arterial de O 2 (GOMES et al, 2019;KHATONY et al, 2019).…”

Section: Considerações Finaisunclassified

“…Análise descritiva dos estudos publicados entre 2015 e 2020 que aborda a influencia do posicionamento nos prematuros internados em unidades de terapia intensiva.DISCUSSÃOOs resultados deste estudo retratam a escassez relacionada à forma que o posicionamento interfere na rotina e desenvolvimento do prematuro internado em unidade de terapia intensiva, entendendo-se apenas doze estudos contemplaram os critérios de elegibilidades. A amostra dos estudos avaliados variavade 15 (BELL et al, 2017) a 135(ALTMIS et al, 2018)picking up, sit and stand-up, socket tests in addition to climbing up and down stairs, ten metres walk, and timed up and go (TUG, sugerindo uma maior homogeneidade e robustez em novos estudos.Dentre as medidas avaliadas pelos estudos, podendo observar grande variação e heterogeneidade desses desfechos, tais como frequência cardíaca(YIN et al, 2015), atividade parassimpática(GOMES et al, 2019), níveis de pepsinaAT (ALY et al, 2015), nível de cortisol, estresse(KAHRAMAN et al, 2017), nível de nutrientes(KHATONY et al, 2019), entre outros. Além disso, pode-se observar que a maioria dos estudos não tiveram diferenças significativas quando comparadas aos grupos.…”

unclassified

“…Foram estudadas diferentes posições, tais como prona, supina e lateral.O posicionamento é uma estratégia dentro das UTIN, sendo baseada na organização neurocomportamental do recém-nascido, com objetivo de melhorar os sistemas e interação dele como o ambiente(MENGER et al, 2021). Nossos achados mostraram que a posição prona aumentou a atividade parassimpática(GOMES et al, 2019), reduziu dor, estresse, tempo de choro e cortisol salivar(KAHRAMAN et al, 2017) e menor volume residual gástrico(KHATONY et al ., 2019). Segundo PENG et al, 2014a total of 22 preterm infants were enrolled.…”

unclassified

See 2 more Smart Citations

Análise Do Índice De Hiperóxia Em Adultos Na Unidade De Terapia Intensiva Em Hospital Universitário No Estado De São Paulo

Franco¹,

Siqueira²,

Tonella³

et al. 2021

Fisioterapia E Terapia Ocupacional: Promoção &Amp; Prevenção E Reabilitação

View full text Add to dashboard Cite

Direitos para esta edição cedidos à Atena Editora pelos autores. Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0).O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais. Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação com base em critérios de neutralidade e imparcialidade acadêmica.A Atena Editora é comprometida em garantir a integridade editorial em todas as etapas do processo de publicação, evitando plágio, dados ou resultados fraudulentos e impedindo que interesses financeiros comprometam os padrões éticos da publicação. Situações suspeitas de má conduta científica serão investigadas sob o mais alto padrão de rigor acadêmico e ético.

show abstract

Effect of different positions on gastric residuals in preterm infants initiating full enteral feeding

et al. 2021

View full text Add to dashboard Cite

Background This study was conducted to determine the effect of feeding in different positions on the gastric residual volume after feeding in preterm infants who initiated full enteral feeding. Methods This quasi‐experimental study was conducted with the hypothesis that testing the right lateral position leads to less gastric residual than left lateral position and the prone position leads to less gastric residual than the supine position. The data were collected in four stages from 35 preterm infants. Initially, the infants were positioned in supine position and were fed. After feeding, the infant rested in the supine position for 3 h. The stomach content was aspirated, and the volume of gastric residual was measured at the 60th, 120th, and 180th min after feeding. These steps are repeated in order of in the right lateral, left lateral, and prone position. Total gastric residual volume and type of enteral feeding were evaluated. Results There was no significant difference among the positions in terms of the volume of gastric residuals in the measurements made at 60th (P = 9.552), 120th (P = .505), and 180th min (P = .430). When the amount of decrease in the gastric residual volumes was a significant difference between all measurement times in right lateral and prone positions (P < .001). Conclusion Although no significant difference was determined between the positions, the smallest residual volumes were determined in the right lateral and prone positions. The amount of decrease in residual volume was significant in right lateral and prone positions.

show abstract

The effects of position on gastric residual volume of premature infants in NICU

Cited by 15 publications

References 13 publications

Real-World Outcomes of Ivacaftor Treatment in People with Cystic Fibrosis: A Systematic Review

Real-World Outcomes of Ivacaftor Treatment in People with Cystic Fibrosis: A Systematic Review

Análise Do Índice De Hiperóxia Em Adultos Na Unidade De Terapia Intensiva Em Hospital Universitário No Estado De São Paulo

Effect of different positions on gastric residuals in preterm infants initiating full enteral feeding

Contact Info

Product

Resources

About