The effects of polyvinyl alcohol-coated selenium nanoparticles on memory impairment in rats

Hashemi-Firouzi, Nasrin; Afshar, Simin; Asl, Sara Soleimani; Samzadeh‐Kermani, Alireza; Gholamigeravand, Bahareh; Amiri, Kimia; Majidi, Mahsa; Shahidi, Siamak

doi:10.1007/s11011-022-01084-4

Cited by 8 publications

(5 citation statements)

References 66 publications

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“…Baldinotti and others [211] reported that in a mouse model of AD induced by intracerebroventricular (ICV) infusion of STZ, intragastric pretreatment with selenium in the form of octylseleno-xylofuranoside can prevent cognitive and memory decline that may be mediated by decreased lipid peroxidation and its modulatory effects on neurotransmission, as evidenced by changes in acetylcholinesterase and monoamine oxidase. Using a similar STZ-induced AD model in rats, Hashemi-Firouzi and others also demonstrated that oral gavage of selenium nanoparticles (SeNP) or polyvinyl alcohol-coated SeNP for one month significantly enhanced hippocampal BDNF and TAC, lowered malondialdehyde and amyloid plaques, as well as markedly alleviated cognitive and memory deficits as assessed by novel object recognition and passive avoidance learning tests [212]. SeNP was also shown for its ability to enter cells via endocytosis in Aβ-treated PC12 cells to effectively inhibit ROS and inflammatory and apoptotic responses while promoting expressions of BDNF and phosphorylation of AKT and CREB [250].…”

Section: Seleniummentioning

confidence: 96%

“…Lowers risk of cognitive impairment [190,191] ↓ Aβ, ↓ pTau, ↑ cognition [192][193][194][195][196][197] Se ↓ Aβ [198], associated with improved cognition [199][200][201] or cognitive dysfunction [202,203] ↓ Aβ, ↓ pTau, ↑ cognition [204][205][206][207][208][209][210][211][212][213] Fe Associated with cognitive impairment [214] or no association with AD risk [215] ↓ Cognition [216], ↓ Aβ, ↓ pTau [217] Cu Association with increased AD risk [218], ↓ cognition [219] ↓ Aβ, ↓ cognition [220][221][222],…”

Section: Mgmentioning

confidence: 99%

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Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease

et al. 2023

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Alzheimer’s disease (AD) is the most common type of dementia that affects millions of individuals worldwide. It is an irreversible neurodegenerative disorder that is characterized by memory loss, impaired learning and thinking, and difficulty in performing regular daily activities. Despite nearly two decades of collective efforts to develop novel medications that can prevent or halt the disease progression, we remain faced with only a few options with limited effectiveness. There has been a recent growth of interest in the role of nutrition in brain health as we begin to gain a better understanding of what and how nutrients affect hormonal and neural actions that not only can lead to typical cardiovascular or metabolic diseases but also an array of neurological and psychiatric disorders. Vitamins and minerals, also known as micronutrients, are elements that are indispensable for functions including nutrient metabolism, immune surveillance, cell development, neurotransmission, and antioxidant and anti-inflammatory properties. In this review, we provide an overview on some of the most common vitamins and minerals and discuss what current studies have revealed on the link between these essential micronutrients and cognitive performance or AD.

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Section: Seleniummentioning

confidence: 96%

Section: Mgmentioning

confidence: 99%

Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease

et al. 2023

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“…They displayed high BBB permeability and effectively decomposed the preformed Aβ fibrils into nontoxic amorphous oligomers. Other Se NPs also exhibited similar therapeutic effects, such as Se NPs coated with Tet‐1 peptide and stabilized by the epigallocatechin‐3‐gallate (EGCG) (Tet‐1‐EGCG@Se), [ 179 ] the polyvinyl alcohol (PVA)‐coated SeNPs (PVA‐SeNPs), [ 180 ] the chitosan‐coated Se NPs (ChSeNPs), [ 181 ] the quercetin‐loaded Se NPs (P80‐Que@SeNPs), [ 182 ] and the selenium nanoparticles stabilized with chitosan (Ch‐SeNPs) (Table 1). [ 183 ] Furthermore, another Se NPs coated with dihydromyricetin (DMY) (Tg‐CS/DMY@SeNPs) (Table 1) ameliorate neuroinflammation through the gut microbiota‐NLRP3 inflammasome‐brain axis in APP/PS1 mice.…”

Section: Low‐dimensional Nanomaterials For Alzheimer's Disease Treatmentmentioning

confidence: 99%

Alzheimer's Disease: Status of Low‐Dimensional Nanotherapeutic Materials

Huang,

Liao,

et al. 2023

Adv Funct Materials

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Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease that constitutes the third most common cause of death among elderly individuals. AD patients suffer from behavioral problems regularly, like memory loss, thinking deficits, and cognitive disorders. Currently, the incidence rate of AD has been on the rise worldwide. Therefore, it is imperative to develop effective strategies for the treatment and prevention of AD. The inherent characteristics of low‐dimensional nanomaterials, primarily their smaller size and surface structure, make them well‐suited for fulfilling the essential requirements of therapeutic drug design. Consequently, these nanomaterials offer a highly appealing and alternative approach to treating AD. Here, the low‐dimensional nanomaterials used in the treatment of AD to provide new ideas, methods, and comprehensive perspectives for the management of AD are reviewed. This review will advance the comprehensive understanding of the potential of low‐dimensional nanomaterials in the field of neuro medicine, which also will have a positive impact on future research.

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“…The reactions in aqueous media often occur in the presence of certain emulsifiers or surfactants, which create stable colloidal systems that will finally contain the SeNPs. Examples of such stabilizing agents are quaternary ammonium compounds [72], polysaccharides, arabic gum [73], chondroitin sulfate [74], chitosan [75,76], carrageenan [77], lignosulfonate [78]; proteins/peptides, zein [79], beta-lactoglobulin [80], chymotrypsin [81], peanut meal peptides [82], tilapia peptides [83], and polyvinyl alcohol [84]. Physical methods of SeNPs synthesis mainly involve the exposure of selenium precursors to different radiation sources.…”

Section: Introductionmentioning

confidence: 99%

The Clothes Matter—Exploiting Agronomical Functions of Trichogenic Selenium Nanoparticles Sharing Activities with Biological Systems Wherein (Were) Formed

Ciobanu,

Bînzari,

Dima

et al. 2024

Agronomy

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The formation of biogenic selenium nanoparticles (SeNPs) through microbial activities is a promising technique that can contribute to the development of reliable, non-toxic and environmentally friendly synthesis methods. Among these, under optimal conditions, myconanotechnology confers particular characteristics due to the generation of bioactive fungal metabolites with various bioactivities. The formed SeNPs are known to be stabilized by the biomolecules of the microorganism, forming a so-called bio-corona or capping structure. The composition of this bio-corona greatly impacts the SeNPs activity, but investigations have been limited to date. The SeNPs produced by Trichoderma sp. have potential applications in crops and environmental management, as both selenium and Trichoderma are known to benefit cultivated plants and phytoremediation. This review summarizes the biosynthesis of SeNPs by Trichoderma sp. and contextualizes the possible correlations between SeNPs and biomolecules produced by Trichoderma; it also provides a missing analysis that could help understand and optimize this process. Biosynthesis methods and probable mechanisms are briefly discussed as well as the role and applications of trichogenic SeNPs as plant protectants, plant biostimulants, and safe biofortifying agents. The knowledge gaps related to mechanisms of trichogenic SeNPs biosynthesis, the control of the desired characteristics for a specific agricultural function, and technology scale-up are discussed in connection with the needed future research directions.

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The effects of polyvinyl alcohol-coated selenium nanoparticles on memory impairment in rats

Cited by 8 publications

References 66 publications

Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease

Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease

Alzheimer's Disease: Status of Low‐Dimensional Nanotherapeutic Materials

The Clothes Matter—Exploiting Agronomical Functions of Trichogenic Selenium Nanoparticles Sharing Activities with Biological Systems Wherein (Were) Formed

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