The effects of physical activity, fast-mimicking diet and psychological interventions on cancer survival: A systematic review and meta-analysis of randomized controlled trials

Clark, Emma; Maguire, Hannah; Cannon, Paul J.; Leung, Elaine

doi:10.1016/j.ctim.2020.102654

Cited by 6 publications

(2 citation statements)

References 59 publications

(66 reference statements)

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“…Но с другой стороны, достоверные положительные эффекты относятся только к улучшению качества жизни пациентов, а выводы о снижении смертности у больных (не онкологической смертности в общей популяции!) статистически надежны пока еще только для рака молочной железы; касательно других локализаций данные пока недостаточны [103]. Но следует подчеркнуть, что это относится к смертности среди пациентов с уже установленным диагнозом.…”

Section: лечение и реабилитацияunclassified

Three pandemics at once: Noninfectious (cancer), infectious (COVID-19), and behavioral (hypokinesia)

Golubev¹,

Semiglazova²,

Klyuge³

et al. 2021

Problems in oncology

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The narrative review addresses the evidence that physical activity can improve the results of prevention and treatment and of the conditions that feature increased risks of their development with aging. The main attention is paid to cancer and problems arising because of physical activity limitations associated with COVID-19 pandemic. To promote physical activity, which is known to reduce the risks of COVID-19 complications and of cancer, it is important to help patients and physicians in understanding the reasons why physical activity can be beneficial, more than the pharmacological means thought to reproduce some of its effects, in cancer prevention and treatment upon all differences between the locations of tumors and the pathways of carcinogenesis. Therefore, the physiological and molecular mechanisms behind the usefulness of physical activity in oncology are discussed. Based on this discussion, data on quantitative relationships between oncological risks, physical activity, and the use of its alleged pharmacological mimetics are addressed.

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Section: лечение и реабилитацияunclassified

Three pandemics at once: Noninfectious (cancer), infectious (COVID-19), and behavioral (hypokinesia)

Golubev¹,

Semiglazova²,

Klyuge³

et al. 2021

Problems in oncology

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“…Lifestyle factors are of particular interest to clinicians, as they allow outcomes to not only be predicted, but to be potentially manipulated as well. This aspect of non-pharmacological interventions in oncology is indeed rising growing interest recently ( 13 , 14 ). In this review, we critically summarise existing evidence on key lifestyle factors of interest – diet, physical exercise, and bright light exposure – with regards to ICI efficacy, through CTS manipulation, and impact on the immune system and the microbiome.…”

Section: Introductionmentioning

confidence: 99%

Circadian lifestyle determinants of immune checkpoint inhibitor efficacy

Hughes,

Shanaz,

Ismail-Sutton

et al. 2023

Front. Oncol.

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Immune Checkpoint Inhibitors (ICI) have revolutionised cancer care in recent years. Despite a global improvement in the efficacy and tolerability of systemic anticancer treatments, a sizeable proportion of patients still do not benefit maximally from ICI. Extensive research has been undertaken to reveal the immune- and cancer-related mechanisms underlying resistance and response to ICI, yet more limited investigations have explored potentially modifiable lifestyle host factors and their impact on ICI efficacy and tolerability. Moreover, multiple trials have reported a marked and coherent effect of time-of-day ICI administration and patients’ outcomes. The biological circadian clock indeed temporally controls multiple aspects of the immune system, both directly and through mediation of timing of lifestyle actions, including food intake, physical exercise, exposure to bright light and sleep. These factors potentially modulate the immune response also through the microbiome, emerging as an important mediator of a patient’s immune system. Thus, this review will look at critically amalgamating the existing clinical and experimental evidence to postulate how modifiable lifestyle factors could be used to improve the outcomes of cancer patients on immunotherapy through appropriate and individualised entrainment of the circadian timing system and temporal orchestration of the immune system functions.

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Fast Mimicking Diets and Other Innovative Nutritional Interventions to Treat Patients with Breast Cancer

Giugliano,

Boldrini,

Uliano

et al. 2023

Cancer Treatment and Research

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The effects of physical activity, fast-mimicking diet and psychological interventions on cancer survival: A systematic review and meta-analysis of randomized controlled trials

Cited by 6 publications

References 59 publications

Three pandemics at once: Noninfectious (cancer), infectious (COVID-19), and behavioral (hypokinesia)

Three pandemics at once: Noninfectious (cancer), infectious (COVID-19), and behavioral (hypokinesia)

Circadian lifestyle determinants of immune checkpoint inhibitor efficacy

Fast Mimicking Diets and Other Innovative Nutritional Interventions to Treat Patients with Breast Cancer

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