The Effects of Pain, Gender, and Age on Sleep/Wake and Circadian Rhythm Parameters in Oncology Patients at the Initiation of Radiation Therapy

Buffum, David; Koetters, Theresa; Cho, Maria; Macera, Liz; Paul, Steven M.; West, Claudia; Aouizerat, Bradley E.; Dunn, Laura B.; Dodd, Marylin; Lee, Kathryn; Cooper, Bruce A.; Wara, William; Swift, Patrick S.; Miaskowski, Christine

doi:10.1016/j.jpain.2010.09.008

Cited by 27 publications

(17 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The number of participants in the control groups (including cancer and noncancer) evaluated in studies was 1607. Only 90 studies (35%) included a comparison group in the study design, with most comparison groups being subjects with cancer.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Systematic review of sleep disorders in cancer patients: can the prevalence of sleep disorders be ascertained?

et al. 2014

View full text Add to dashboard Cite

Although sleep is vital to all human functioning and poor sleep is a known problem in cancer, it is unclear whether the overall prevalence of the various types of sleep disorders in cancer is known. The purpose of this systematic literature review was to evaluate if the prevalence of sleep disorders could be ascertained from the current body of literature regarding sleep in cancer. This was a critical and systematic review of peer-reviewed, English-language, original articles published from 1980 through 15 October 2013, identified using electronic search engines, a set of key words, and prespecified inclusion and exclusion criteria. Information from 254 full-text, English-language articles was abstracted onto a paper checklist by one reviewer, with a second reviewer randomly verifying 50% (k = 99%). All abstracted data were entered into an electronic database, verified for accuracy, and analyzed using descriptive statistics and frequencies in SPSS (v.20) (North Castle, NY). Studies of sleep and cancer focus on specific types of symptoms of poor sleep, and there are no published prevalence studies that focus on underlying sleep disorders. Challenging the current paradigm of the way sleep is studied in cancer could produce better clinical screening tools for use in oncology clinics leading to better triaging of patients with sleep complaints to sleep specialists, and overall improvement in sleep quality.

show abstract

Section: Resultsmentioning

confidence: 99%

“…When selecting participants for studies, potentially important inclusion and exclusion criteria for sleep were rarely addressed. For example, only 19.7% ( n = 50) of the studies reviewed excluded for previous sleep disorder or current treatment of sleep disorders.…”

Section: Resultsmentioning

confidence: 99%

Systematic review of sleep disorders in cancer patients: can the prevalence of sleep disorders be ascertained?

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Since these patients were evaluated prior to receiving their next dose of CTX, these between group differences suggest that CP is associated with increases in morning fatigue. Since pain is known to disrupt sleep, 17 these relatively high levels of morning fatigue may be related to the higher levels of both pain and sleep disturbance reported by these patients.…”

Section: Discussionmentioning

confidence: 97%

Differences in demographic, clinical, and symptom characteristics and quality of life outcomes among oncology patients with different types of pain

Posternak¹,

Dunn

Dhruva

et al. 2016

Pain

Self Cite

View full text Add to dashboard Cite

The purposes of this study, in oncology outpatients receiving chemotherapy (CTX, n=926), were to: describe the occurrence of different types of pain (i.e., no pain, only non-cancer pain (NCP), only cancer pain (CP), or both CP and NCP) and evaluate for differences in demographic, clinical, and symptom characteristics, and quality of life (QOL) among the four groups. Patients completed self-report questionnaires on demographic and symptom characteristics and QOL. Patients who had pain were asked to indicate if it was or was not related to their cancer or its treatment. Medical records were reviewed for information on cancer and its treatments. In this study, 72.5% of the patients reported pain. Of the 671 who reported pain, 21.5% reported only NCP, 37.0% only CP, and 41.5% both CP and NCP. Across the three pain groups, worst pain scores were in the moderate to severe range. Compared to the no pain group, patients with both CP and NCP were significantly younger, more likely to be female, have a higher level of comorbidity and a poorer functional status. In addition, these patients reported: higher levels of depression, anxiety, fatigue, and sleep disturbance; lower levels of energy and attentional function; and poorer QOL. Patients with only NCP were significantly older than the other three groups. The most common comorbidities in the NCP group were back pain, hypertension, osteoarthritis, and depression. Unrelieved CP and NCP continue to be significant problems. Oncology outpatients need to be assessed for both CP and NCP conditions.

show abstract

“…Neuropathic pain can be associated with insomnia symptoms (Smith and Haythornthwaite, 2004). Previous studies have indicated a reciprocal association between chronic pain and sleep disturbance in various medical conditions, such as cancers, angina, renal failure, fibromyalgia, arthritis and musculoskeletal strains (Buffum et al, 2011;Edinger et al, 2005;Wilson et al, 1998). Increased daytime pain has been associated with poor night-time sleep and poor sleep is associated, in turn, with augmented next-day pain.…”

Section: Discussionmentioning

confidence: 99%

Various patterns of disrupted daily rest–activity rhythmicity associated with diabetes

Kadono

Nakanishi

Yamazaki

et al. 2016

Journal of Sleep Research

View full text Add to dashboard Cite

SUMMARYDisruptions to sleep and circadian rhythms have now been recognized as common comorbidities in patients with medical illnesses. We aimed to determine if the diurnal rhythms for rest and activity were disrupted in parallel with the development of diabetic complications. Ninety outpatients in our diabetes clinic who had a body mass index <25 kg m 2 wore an actigraph for 7 consecutive days (42 men; mean age 68.7 AE 8.2 years). Patients with neuropsychiatric diseases, liver cirrhosis, renal failure, chronic obstructive pulmonary disease or blindness, or those who performed shiftwork were excluded. We grouped the actigraph recordings into 1-h periods and counted the number of minutes that showed activity. Stepwise regression analysis showed an association between a diabetic clinical background and measurements of circadian rhythms such as daytime activity, night-time activity, phase, interdaily stability, intradaily variability and relative amplitude. Higher age, body mass index, total cholesterol levels and insulin usage were associated with lower daytime activity and higher intradaily variability, whereas higher haemoglobin A1c levels and the presence of neuropathy were associated with greater daytime activity. The presence of proliferative retinopathy and increased levels of microalbuminuria were associated with higher intradaily variability and lower interdaily stability and amplitude. The presence of cardiovascular disease was associated with advanced phase, whereas painful neuropathy was associated with delayed phase. Our study demonstrated that different diabetic complications were associated independently with a variety of alterations in the circadian rest and activity rhythms. Our findings have provided novel insights that may be helpful in developing interventions for sleep-wake disorders associated with diabetes.

show abstract

The Effects of Pain, Gender, and Age on Sleep/Wake and Circadian Rhythm Parameters in Oncology Patients at the Initiation of Radiation Therapy

Cited by 27 publications

References 65 publications

Systematic review of sleep disorders in cancer patients: can the prevalence of sleep disorders be ascertained?

Systematic review of sleep disorders in cancer patients: can the prevalence of sleep disorders be ascertained?

Differences in demographic, clinical, and symptom characteristics and quality of life outcomes among oncology patients with different types of pain

Various patterns of disrupted daily rest–activity rhythmicity associated with diabetes

Contact Info

Product

Resources

About